News tagged with channel protein
Gene discovery explains how fruit flies retreat from heat
A discovery in fruit flies may be able to tell us more about how animals, including humans, sense potentially dangerous discomforts.
Dec 15, 2011 |
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Researcher develops model to foster new drug development to treat pain and epilepsy
Drawing on X-ray crystallography and experimental data, as well as a software suite for predicting and designing protein structures, a UC Davis School of Medicine researcher has developed an algorithm that predicts what has ...
Dec 12, 2011 |
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Scientists merge spider silk, human muscle to design a novel, self-assembling peptide
(Medical Xpress) -- Because of its high water content and polymer network, peptide hydrogel is a promising material for protein storage and transfer without significant loss of their biological activity. These hydrogels have ...
Dec 02, 2011 |
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Neurons grown from skin cells may hold clues to autism
Potential clues to how autism miswires the brain are emerging from a study of a rare, purely genetic form of the disorders that affects fewer than 20 people worldwide. Using cutting-edge "disease-in a-dish" ...
Nov 27, 2011 |
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Researchers identify key proteins of inner ear transduction channel
National Institutes of Health-funded researchers have identified two proteins that may be the key components of the long-sought after mechanotransduction channel in the inner ear—the place where the mechanical stimulation ...
Nov 21, 2011 |
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Study shows Alzheimer's disease-related peptides form toxic calcium channels in the plasma membrane
Alzheimer's disease is triggered by the inappropriate processing of amyloid precursor protein to generate excess amounts of short peptide fragments called A-beta. For many years, the neurodegeneration associated with Alzheimer's ...
Oct 24, 2011 |
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Abnormal activation of a protein may explain deadly link between high salt intake and obesity
Dietary salt intake and obesity are two important risk factors in the development of high blood pressure. Each packs its own punch, but when combined, they deliver more damage to the heart and kidneys than the sum of their ...
Sep 19, 2011 |
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Unraveling a new regulator of cystic fibrosis
Cystic fibrosis (CF), a chronic disease that clogs the lungs and leads to life-threatening lung infections, is caused by a genetic defect in a chloride channel called cystic fibrosis transmembrane conductase regulator (CFTR). ...
Sep 19, 2011 |
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An 'unconventional' path to correcting cystic fibrosis
Researchers have identified an unconventional path that may correct the defect underlying cystic fibrosis, according to a report in the September 2nd issue of the journal Cell. This new treatment dramatically extends the li ...
Sep 01, 2011 |
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Timothy syndrome mutations provide new insights into the structure of L-calcium channel
The human genome encodes 243 voltage-gated ion channels. Mutations in calcium channels can cause severe inherited diseases such as migraine, night blindness, autism spectrum disorders and Timothy syndrome, ...
Jul 14, 2011 |
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Cell's power generator depends on long-sought protein: 50-year search for calcium channel ends
(PhysOrg.com) -- Mitochondria, those battery-pack organelles that fuel the energy of almost every living cell, have an insatiable appetite for calcium. Whether in a dish or a living organism, the mitochondria ...
Jun 19, 2011 |
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Researchers find new 'molecular motors' that bacteria use to transport proteins
(PhysOrg.com) -- Joshua Shaevitz, an assistant professor from the Department of Physics and the Lewis-Sigler Institute for Integrative Genomics at Princeton University, along with Mingzhai Sun, a postdoctoral associate at ...
Jun 13, 2011 |
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Small change makes a big difference for ion channels
Using a high-resolution single-molecule study technique, University of Illinois researchers have seen the very subtle differences between two branches of an important family of neurotransmitter-gated ion channels.
Jun 02, 2011 |
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Researchers get a first look at the mechanics of membrane proteins
In two new studies, researchers provide the first detailed view of the elaborate chemical and mechanical interactions that allow the ribosome – the cell's protein-building machinery – to insert a ...
Apr 17, 2011 |
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Potassium channel gene modifies risk for epilepsy
Vanderbilt University researchers have identified a new gene that can influence a person's risk for developing epilepsy. The findings, reported in the March 29 Proceedings of the National Academy of Sciences, could improv ...
Apr 04, 2011 |
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