News tagged with checkpoint proteins
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Search results for checkpoint proteins
Chemists Discover How Cells Create Stability During Critical DNA-to-RNA Information Transfers
19 hours ago |
4.5 / 5 (11) |
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(PhysOrg.com) -- A pair of University of Massachusetts Amherst chemists believe they have for the first time explained how the main players in transcription -- RNA polymerase, RNA (red in illustration) and ...
Scientists Show How Bacteria Move Electrons Across a Membrane
23 hours ago |
4.6 / 5 (7) |
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(PhysOrg.com) -- Scientists at the University of East Anglia, Pacific Northwest National Laboratory, and Pennsylvania State University have demonstrated for the first time the mechanism by which some bacteria ...
New research could advance research field critical to personalized medicine
Dec 29, 2009 |
5 / 5 (2) |
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It's the ultimate goal in the treatment of cancer: tailoring a person's therapy based on his or her genetic makeup. While a lofty goal, scientists are steadily moving forward, rapidly exploiting new technologies. Researchers ...
Common mechanism underlies many diseases of excitability
Dec 28, 2009 |
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Inherited mutations in voltage-gated sodium channels (Navs) are associated with many different human diseases, including genetic forms of epilepsy and chronic pain. Theodore Cummins and colleagues, at Indiana University School ...
'Notch'ing up a role in the multisystem disease tuberous sclerosis complex
Dec 28, 2009 |
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Two independent teams of researchers have identified a role for enhanced activation of the signaling protein Notch in tumors characterized by inactivation of either the TSC1 or the TSC2 protein. As indicated by Warren Pear, ...
Simplest bacteria unravelled at the cellular level
Dec 28, 2009 |
4.8 / 5 (4) |
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Even the simplest cell appears to be far more complex than researchers had imagined. In a series of three articles in the journal Science, researchers including Vera van Noort at the European Molecular Biology Laboratory (EMBL) ...
Molecular chaperone keeps bacterial proteins from slow-dancing to destruction
Dec 28, 2009 |
4 / 5 (1) |
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Just like teenagers at a prom, proteins are tended by chaperones whose job it is to prevent unwanted interactions among immature clients. And at the molecular level, just as at the high school gym level, it's a job that usually ...
One step closer to closure: Neuroscientists discovery key to spinal cord defects
Medicine & Health / Neuroscience
Dec 28, 2009 |
5 / 5 (3) |
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Spinal cord disorders like spina bifida arise during early development when future spinal cord cells growing in a flat layer fail to roll up into a tube. In the Dec. 6 issue of Nature Cell Biology, researchers from the Jo ...
BBS proteins shown to run an export business that protects cilia
Dec 28, 2009 |
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A protein complex mutated in human disease removes excess signaling molecules to prevent them from damaging cilia, say researchers from UMass Medical School. The study will be published in the December 28 ...
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