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Chemotherapy

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Chemotherapy, in its most general sense, refers to treatment of disease by chemicals that kill cells, both good and bad, but specifically those of micro-organisms or cancerous tumours. In popular usage, it refers to antineoplastic drugs used to treat cancer or the combination of these drugs into a cytotoxic standardized treatment regimen. In its non-oncological use, the term may also refer to antibiotics (antibacterial chemotherapy). In that sense, the first modern chemotherapeutic agent was Paul Ehrlich's arsphenamine, an arsenic compound discovered in 1909 and used to treat syphilis. This was later followed by sulfonamides discovered by Domagk and penicillin discovered by Alexander Fleming.

Most commonly, chemotherapy acts by killing cells that divide rapidly, one of the main properties of cancer cells. This means that it also harms cells that divide rapidly under normal circumstances: cells in the bone marrow, digestive tract and hair follicles; this results in the most common side effects of chemotherapy—myelosuppression (decreased production of blood cells), mucositis (inflammation of the lining of the digestive tract) and alopecia (hair loss).

Other uses of cytostatic chemotherapy agents (including the ones mentioned below) are the treatment of autoimmune diseases such as multiple sclerosis and rheumatoid arthritis and the suppression of transplant rejections (see immunosuppression and DMARDs). Newer anticancer drugs act directly against abnormal proteins in cancer cells; this is termed targeted therapy.

For more information about Chemotherapy, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.


News tagged with chemotherapy


Gefitinib improves survival compared with standard chemotherapy in lung cancer patients with genetic mutation

Medicine & Health / Cancer

created Dec 20, 2009 | popularity 5 / 5 (1) | comments 0

Patients with the most common form of lung cancer (non-small-cell lung cancer) who have mutations in the epidermal growth factor receptor (EGFR) gene have significantly improved progression-free survival if they are treated ...


Study reveals chemo's toxicity to brain, possible treatment

Medicine & Health / Cancer

created Dec 17, 2009 | popularity 5 / 5 (2) | comments 0

Researchers have developed a novel animal model showing that four commonly used chemotherapy drugs disrupt the birth of new brain cells, and that the condition could be partially reversed with the growth factor IGF-1.





Search results for chemotherapy


Protein link may be key to new treatment for aggressive brain tumor

Protein link may be key to new treatment for aggressive brain tumor

Medicine & Health / Cancer

created 14 hours ago | popularity 5 / 5 (1) | comments 0

Biomedical researchers at the University of Central Florida have found a protein that could hold the key to treating one of the most common and aggressive brain tumors in adults.


Chicago Cancer Genome Project studies genetics of 1,000 tumors

Medicine & Health / Genetics

created 15 hours ago | popularity 5 / 5 (2) | comments 0

No two tumors are alike, but analyzing the genetics of cancers from different parts of the body may reveal surprising details useful for treatment and prevention.


Enzyme necessary for development of healthy immune system

Medicine & Health / Research

created 16 hours ago | popularity not rated yet | comments 0

Mice without the deoxycytidine kinase (dCK) enzyme have defects in their adaptive immune system, producing very low levels of both T and B lymphocytes, the major players involved in immune response, according to a study by ...


Adding a genetic supertool: Genome Analyzer fuels research dreams and tomorrow's cures

Medicine & Health / Genetics

created 17 hours ago | popularity not rated yet | comments 0

To identify the hemophilia mutation that affected Queen Victoria and her European relatives, scientific detectives used a cutting-edge "deep sequencing tool." Able to trace rare genetic disease mutations, the tool can turn ...


Researchers Identify Tuberculosis Strain That Thrives on Antibiotic

Medicine & Health / Diseases

created Dec 21, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- Scientists have identified a strain of antibiotic-resistant tuberculosis that thrives in the presence of rifampin, a front-line drug in the treatment of tuberculosis. The bacterium was identified in a patient ...


Drug for Multiple Myeloma Demonstrated to Significantly Extend Disease-Free Survival

Medicine & Health / Cancer

created Dec 21, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- Initial results from a large, randomized clinical trial for patients with multiple myeloma, a cancer of the blood and bone marrow, showed that patients who received the oral drug lenalidomide (Revlimid, also ...


Protein inhibits cancer cell growth

Medicine & Health / Cancer

created Dec 21, 2009 | popularity 5 / 5 (2) | comments 0

(PhysOrg.com) -- Researchers at the University of Toronto and Goethe University in Germany have discovered a protein that can inhibit the growth of cancer cells, providing crucial clues for the future development of new drugs ...


Gene linked to a rare form of progressive hearing loss in males is identified

Medicine & Health / Genetics

created Dec 17, 2009 | popularity not rated yet | comments 0

A gene associated with a rare form of progressive deafness in males has been identified by an international team of researchers funded by the National Institute on Deafness and Other Communication Disorders. The gene, PRPS1, ...


Heart drugs show promise for fighting colon cancer

Heart drugs show promise for fighting colon cancer

Medicine & Health / Cancer

created Dec 16, 2009 | popularity not rated yet | comments 0

Scientists in Sweden are reporting for the first time that a group of drugs used to treat heart failure shows promise for fighting colon cancer. The study is in ACS' Journal of Natural Products. Colon cancer ...



List of search results for chemotherapy