News tagged with chromatin
Singapore scientists describe novel method for 3-D whole genome mapping research
Nov 04, 2009 |
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In this week's Nature, Genome Institute of Singapore (GIS) scientists report a technological advance in the study of gene expression and regulation in the genome's three-dimensional folding and looping state through the de ...
Aurora B answers an XIST-ential question
Aug 24, 2009 |
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Early in development, mammalian female cells counteract their double dose of X chromosomes by coating one of them with a large RNA named XIST. The RNA binds to the same X chromosome from which it is transcribed ...
Scientists uncover function of potential cancer-causing gene product
Aug 09, 2009 |
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The Stowers Institute's Conaway Lab has uncovered a previously unknown function of a gene product called Amplified in Liver Cancer 1 (Alc1), which may play a role in the onset of cancer. The work was published yesterday by ...
UCSD Engineer Provides Insights to Decades-Old DNA Squabble
Jul 31, 2009 |
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(PhysOrg.com) -- A group of nanoengineers, biologists and physicists have used innovative approaches to deduce the internal structure of chromatin, a key player in DNA regulation, to reconcile a longstanding ...
BRIT1 allows DNA repair teams access to damaged sites
Jun 19, 2009 |
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Like a mechanic popping the hood of a car to get at a faulty engine, a tumor-suppressing protein allows cellular repair mechanisms to pounce on damaged DNA by overcoming a barrier to DNA access.
Good fences make good neighbors
May 14, 2009 |
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Our genome is a patchwork of neighborhoods that couldn't be more different: Some areas are hustling and bustling with gene activity, while others are sparsely populated and in perpetual lock-down. Breaking ...
SUMO protein guides chromatin remodeler to suppress genes
Apr 27, 2009 |
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In an in vitro study, led by Grace Gill, PhD, Tufts University School of Medicine, researchers discovered how a protein called SUMO (Small Ubiquitin-related Modifier) guides an enzyme complex that alters the structure of ...
Protein complex shown to play pivotal role in stem cell development in 2 Stanford studies
Mar 02, 2009 |
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Scientists at the Stanford University School of Medicine have identified a protein complex important in controlling whether embryonic stem cells retain their ability to become any cell in the body — a quality called pluripotency ...
Tracking the molecular pathway to mixed-lineage leukemia
Dec 15, 2008 |
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Infants and adults with the blood cancer mixed-lineage leukemia (MLL) typically have a poor prognosis, and most infants die before their first birthdays. Although there are varying causes of MLL, most cases are caused by ...
