Using glowing fish to detect harmful pesticides

Birth defects related to chromosomal abnormalities often stem from exposure to chemicals early in the mother's life. But determining which chemicals are at fault poses a serious challenge—akin to solving a hit-and-run case, ...

Study finds why many IVF embryos fail to develop

In humans, a fertilized egg is no guarantee of reproductive success. Most embryos stop developing and perish within days of fertilization, usually because they have an abnormal number of chromosomes. Now, researchers at Columbia ...

How to find mutated sperm? Just go FISH

Chemotherapy and radiation treatments are known to cause harsh side effects that patients can see or feel throughout their bodies. Yet there are additional, unseen and often undiscussed consequences of these important therapies: ...

Why premature cell division promotes cancers

The accumulation of mutations in the human genome is at the origin of cancers, as well as the development of resistance to treatments. The Cyclin E and Myc genes are active in the control of cell division. When they mutate ...

Scientists overcome pig genome flaw

Through her work, Dr Rebecca O'Connor in the School of Biosciences, found previously undiscovered, fundamental flaws in the pig genome, the results of which have contributed to improved mapping of the pig genome.

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Chromosome abnormality

A chromosome anomaly (chromosome abnormality) reflects an atypical number of chromosomes (karyotype) or a structural abnormality in one or more chromosomes. Chromosome anomalies usually occur when there is an error in cell division following meiosis or mitosis. There are many types of chromosome anomalies. They can be organized into two basic groups, numerical and structural anomalies.

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