Chronic obstructive pulmonary disease
hideChronic obstructive pulmonary disease (COPD) refers to chronic bronchitis and emphysema, a pair of two commonly co-existing diseases of the lungs in which the airways become narrowed. This leads to a limitation of the flow of air to and from the lungs causing shortness of breath. In contrast to asthma, the limitation of airflow is poorly reversible and usually gets progressively worse over time.
COPD is caused by noxious particles or gas, most commonly from smoking, which trigger an abnormal inflammatory response in the lung. The inflammatory response in the larger airways is known as chronic bronchitis, which is diagnosed clinically when people regularly cough up sputum. In the alveoli, the inflammatory response causes destruction of the tissues of the lung, a process known as emphysema. The natural course of COPD is characterized by occasional sudden worsenings of symptoms called acute exacerbations, most of which are caused by infections or air pollution.
The diagnosis of COPD requires lung function tests. Important management strategies are smoking cessation, vaccinations, rehabilitation, and drug therapy (often using inhalers). Some patients go on to requiring long-term oxygen therapy or lung transplantation.
Worldwide, COPD ranked sixth as the cause of death in 1990. It is projected to be the third leading cause of death worldwide by 2020 due to an increase in smoking rates and demographic changes in many countries. COPD is the 4th leading cause of death in the U.S., and the economic burden of COPD in the U.S. in 2007 was $42.6 billion in health care costs and lost productivity.
COPD is also known as chronic obstructive lung disease (COLD), chronic obstructive airway disease (COAD), chronic airflow limitation (CAL) and chronic obstructive respiratory disease.
For more information about Chronic obstructive pulmonary disease, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
News tagged with chronic obstructive pulmonary disease
Scientists discover genetic pattern that indicates early-stage lung cancer
Dec 01, 2009 |
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Wistar Institute researchers and collaborators from the University of Pennsylvania and New York University have identified immune system markers in the blood which indicate early-stage lung tumors in people at high risk for ...
Wide Disparities Found in Age of Hospitalization for Patients of Different Races
Dec 01, 2009 |
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(PhysOrg.com) -- New research from Yale School of Public Health shows that blacks are admitted to the hospital at a significantly younger age than their white peers for a host of preventable medical conditions, ...
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Weight loss reduces sleep problems in obese men
Dec 04, 2009 |
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Weight loss reduces obstructive sleep apnoea in obese men, with the greatest effect seen in patients with severe disease, according to new research published in the British Medical Journal today.
H1N1 more risky than seasonal flu in children with sickle cell disease
23 minutes ago |
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Infection with the H1N1 virus, or swine flu, causes more life-threatening complications than seasonal flu in children with sickle cell disease, according to research from Johns Hopkins Children's Center. The findings, to ...
Bone Marrow Stem Cells May Prevent Chronic Lung Disease
Dec 01, 2009 |
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(PhysOrg.com) -- Researchers at Children's Hospital Boston have discovered a possible way to protect the fragile lungs of premature babies by using stem cells harvested from bone marrow. In experiments on laboratory mice, ...
Drug shows promise for T315I-mutated chronic myeloid leukemia
43 minutes ago |
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Results from a phase II clinical trial indicate a novel drug may provide a treatment option for chronic myeloid leukemia (CML) patients who do not respond to current therapies, researchers from The University of Texas M. ...
High urea levels in chronic kidney failure might be toxic after all
Dec 02, 2009 |
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It is thought that the elevated levels of urea (the byproduct of protein breakdown that is excreted in the urine) in patients with end-stage kidney failure are not particularly toxic.
Soy peptide lunasin has anti-cancer, anti-inflammatory properties
Dec 02, 2009 |
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Two new University of Illinois studies report that lunasin, a soy peptide often discarded in the waste streams of soy-processing plants, may have important health benefits that include fighting leukemia and blocking the inflammation ...
Why we outlive our ape ancestors
Dec 02, 2009 |
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In spite of their genetic similarity to humans, chimpanzees and great apes have maximum lifespans that rarely exceed 50 years. The difference, explains USC Davis School of Gerontology Professor Caleb Finch, is that as humans ...
Species down, disease up: Study shows biodiversity loss drives human infections
Dec 03, 2009 |
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The extinction of plant and animal species can be likened to emptying a museum of its collection, or dumping a cabinet full of potential medicines into the trash, or replacing every local cuisine with McDonald's burgers.
Aspirin, tylenol may decrease effectiveness of vaccines
Dec 01, 2009 |
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With flu season in full swing and the threat of H1N1 looming, demand for vaccines is at an all-time high. Although those vaccines are expected to be effective, University of Missouri researchers have found further evidence ...
Coverage of inexpensive drugs may increase length and quality of life after heart attack
Nov 30, 2009 |
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Providing free medications to people after heart attack could add years to patients' lives at a relatively low cost for provincial governments, according to a new study by researchers at St. Michael's Hospital in Toronto.
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