Related topics: lung function
Chronic obstructive pulmonary disease
hideChronic obstructive pulmonary disease (COPD) refers to chronic bronchitis and emphysema, a pair of two commonly co-existing diseases of the lungs in which the airways become narrowed. This leads to a limitation of the flow of air to and from the lungs causing shortness of breath. In contrast to asthma, the limitation of airflow is poorly reversible and usually gets progressively worse over time.
COPD is caused by noxious particles or gas, most commonly from smoking, which trigger an abnormal inflammatory response in the lung. The inflammatory response in the larger airways is known as chronic bronchitis, which is diagnosed clinically when people regularly cough up sputum. In the alveoli, the inflammatory response causes destruction of the tissues of the lung, a process known as emphysema. The natural course of COPD is characterized by occasional sudden worsenings of symptoms called acute exacerbations, most of which are caused by infections or air pollution.
The diagnosis of COPD requires lung function tests. Important management strategies are smoking cessation, vaccinations, rehabilitation, and drug therapy (often using inhalers). Some patients go on to requiring long-term oxygen therapy or lung transplantation.
Worldwide, COPD ranked sixth as the cause of death in 1990. It is projected to be the third leading cause of death worldwide by 2020 due to an increase in smoking rates and demographic changes in many countries. COPD is the 4th leading cause of death in the U.S., and the economic burden of COPD in the U.S. in 2007 was $42.6 billion in health care costs and lost productivity.
COPD is also known as chronic obstructive lung disease (COLD), chronic obstructive airway disease (COAD), chronic airflow limitation (CAL) and chronic obstructive respiratory disease.
For more information about Chronic obstructive pulmonary disease, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
News tagged with chronic obstructive pulmonary disease
New genes for lung disease discovered
Dec 13, 2009 |
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(PhysOrg.com) -- Scientists have discovered five genetic variants that are associated with the health of the human lung. The research by an international consortium of 96 scientists from 63 centres in Europe and Australia ...
Gene mutation may reveal clues for treating lung diseases
Oct 15, 2009 |
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(PhysOrg.com) -- A genetic mutation found in four children born with multiple abnormalities may provide insight into potential treatments for newborn lung distress and chronic obstructive pulmonary disease (COPD).
Portable and precise gas sensor could monitor pollution and detect disease
Sep 18, 2009 |
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In the air, it is a serious pollutant. In the body, it plays a role in heart rate, blood flow, nerve signals and immune function. Nitric oxide, a gas well known to scientists for its myriad functions, has ...
Study: Infant inhalation of ultrafine air pollution linked to adult lung disease
Jul 22, 2009 |
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Stephania Cormier, PhD, Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, has shown for the first time that early exposure to environmentally persistent free radicals (present in airborne ultrafine ...
Study: Cigarette smoking does not affect everyone in same way
Jun 04, 2009 |
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Cigarette smoking induced COPD, or chronic obstructive pulmonary disease, is a disease that results in severe breathing difficulty. According to World Health Organization (WHO) it is the fourth leading killer worldwide. However ...
Nanosensor Arrays 'Smell' Cancer
Nanotechnology / Bio & Medicine
Apr 27, 2009 |
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(PhysOrg.com) -- In 2006 researchers established that dogs could detect cancer by sniffing the exhaled breath of cancer patients. Now, using nanoscale arrays of detectors, two groups of investigators have shown that a compact ...
Muscle deterioration in patients with lung disease seen connected to CO2
Apr 23, 2009 |
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Muscle deterioration in patients with lung diseases might be a direct consequence of high carbon dioxide levels in their blood, an international team of researchers headed by Prof. Yosef Gruenbaum of the Hebrew ...
Immune cell activity linked to worsening COPD
Dec 15, 2009 |
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A new study links chronic obstructive pulmonary disease, or COPD, with increased activity of cells that act as sentinels to activate the body's immune system.
Study unveils potential genetic links to lung disease risk
Dec 14, 2009 |
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A new study involving data from more than 20,000 individuals has uncovered several DNA sequences linked to impaired pulmonary function. The research, an analysis that combined the results of several smaller studies, provides ...
Scientists discover genetic pattern that indicates early-stage lung cancer
Dec 01, 2009 |
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Wistar Institute researchers and collaborators from the University of Pennsylvania and New York University have identified immune system markers in the blood which indicate early-stage lung tumors in people at high risk for ...
A new scan for lung diseases
Oct 13, 2009 |
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People with chronic lung disease and asthma could soon be offered better treatment thanks to a new type of Magnetic Resonance Imaging (MRI) scan being pioneered at The University of Nottingham.
Triple therapy halves exacerbations in moderate-to-severe COPD (w/ Podcast)
Oct 08, 2009 |
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Patients with moderate to severe chronic obstructive pulmonary disease (COPD) can benefit from triple therapy that includes a long-acting β-agonist (LABA), an inhaled corticosteroid (ICS) and an anti-muscarinic agent, ...
New tool to predict the risk of death in COPD
Aug 28, 2009 |
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Researchers have developed an index scale to help physicians predict a patient's risk of dying from chronic obstructive pulmonary disease (COPD). The ADO index can help physicians assess the severity of a patient's illness ...
Women more susceptible to harmful effects of smoking
May 18, 2009 |
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Women may be more susceptible to the lung damaging effects of smoking than men, according to new research by Inga-Cecilie Soerheim, M.D., and her colleagues from Channing Laboratory, Brigham and Women's Hospital and University ...
Changes in gene may stunt lung development in children
Medicine & Health / Psychology & Psychiatry
Mar 26, 2009 |
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Mutations in a gene may cause poor lung development in children, making them more vulnerable to diseases such as chronic obstructive pulmonary disease (COPD) later in life, say researchers at the University of Pittsburgh ...
