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News tagged with cisplatin

A silver bullet to beat cancer?

The internet is awash with stories of how silver can be used to treat cancer. Now, lab tests have shown that it is as effective as the leading chemotherapy drug - and may have fewer side-effects.

Medicine & Health / Cancer

created Feb 02, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Radiation plus chemotherapy provides long-term positive results for head and neck cancer patients

A select subgroup of advanced head and neck cancer patients treated with radiation therapy plus the chemotherapy drug cisplatin had more positive outcomes than patients treated with radiation therapy alone and continued to ...

Medicine & Health / Cancer

created Jan 26, 2012 | popularity not rated yet | comments 0

'DIMming' cancer growth -- STAT: Diindolylmethane suppresses ovarian cancer

Ovarian cancer is a major cause of death worldwide. Approximately 25,000 women will be diagnosed with ovarian cancer this year and 15,000 women will die from it in the United States alone. The novel anti-cancer drug diindolylmethane ...

Medicine & Health / Cancer

created Jan 26, 2012 | popularity not rated yet | comments 1

Cancer drug cisplatin found to bind like glue in cellular RNA

An anti-cancer drug used extensively in chemotherapy binds pervasively to RNA -- up to 20-fold more than it does to DNA, a surprise finding that suggests new targeting approaches might be useful, according to University of ...

Chemistry / Biochemistry

created Nov 21, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Inhaled nanoparticles deliver potent anticancer cocktail to lung tumors and block resistance

(PhysOrg.com) -- An ideal treatment for lung cancer would be one that could be inhaled deep into lung tissue where it would deliver tumor-killing agents that would then largely stay in the lungs, avoiding the toxicities that ...

Nanotechnology / Bio & Medicine

created Nov 21, 2011 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Inhaler treatment for lung cancer

Lung cancer patients could receive safer and more efficient treatment through a system being developed by researchers at the University of Strathclyde in Glasgow.

Medicine & Health / Cancer

created Oct 11, 2011 | popularity not rated yet | comments 0

Fish oil reduces effectiveness of chemotherapy

Researchers at University Medical Center Utrecht, the Netherlands, have discovered a substance that has an adverse effect on nearly all types of chemotherapy - making cancer cells insensitive to the treatment. Chemotherapy ...

Medicine & Health / Cancer

created Sep 12, 2011 | popularity 5 / 5 (2) | comments 0

Less-toxic chemo improves outlook for advanced bladder cancer

(Medical Xpress) -- New data from the University of Rochester Medical Center confirms that an easier, two-drug chemotherapy regimen given to bladder cancer patients prior to surgery shrinks locally advanced tumors and completely ...

Medicine & Health / Cancer

created Aug 19, 2011 | popularity not rated yet | comments 0

New drug tested for hereditary breast and ovarian cancers

(Medical Xpress) -- A trial of a new drug for patients with hereditary breast or ovarian cancer at an advanced stage has been launched at the University of Oxford.

Medicine & Health / Cancer

created Aug 17, 2011 | popularity not rated yet | comments 0

Cause and potential treatment found for cancer drug's kidney toxicity

Scientists may have a way to make the powerful cancer drug cisplatin less toxic to the kidneys and more effective against some cancers.

Medicine & Health / Cancer

created Jun 02, 2011 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Curcumin compound improves effectiveness of head and neck cancer treatment

A primary reason that head and neck cancer treatments fail is the tumor cells become resistant to chemotherapy drugs. Now, researchers at the University of Michigan Comprehensive Cancer Center have found that a compound derived ...

Medicine & Health / Cancer

created May 19, 2011 | popularity 4.7 / 5 (3) | comments 0

Cancer cell survival is not 'miR-ly' dependent on p53

Squamous cell carcinoma (SCC) is a common type of skin cancer. In this paper, Leif Ellisen and colleagues at Mass General Hospital investigated the p53-related proteins p63 and p73 in SCC cells, and discovered a feedback ...

Medicine & Health / Cancer

created Jan 10, 2011 | popularity not rated yet | comments 0

Nanoparticles deliver one-two therapeutic punch to kill tumor cells

The standard approach to cancer therapy today is to mix and match chemotherapy drugs in order to attack tumors in multiple ways. Now, two separate teams of investigators have demonstrated that using nanoparticles to deliver ...

Nanotechnology / Bio & Medicine

created Dec 17, 2010 | popularity 4.9 / 5 (7) | comments 1 | with audio podcast

New treatment to overpower drug resistance in ovarian cancer

Drug resistance is a major obstacle in curing ovarian cancer but new research from the Centenary Institute has discovered a treatment that kills ovarian cancer cells in a new way that can break the resistance mechanism. ...

Medicine & Health / Cancer

created Nov 15, 2010 | popularity not rated yet | comments 0

Israel's scientists think big with the very, very small

A material just one atom thick that is stronger than steel but flexes like rubber. A "mini-submarine" that can trick the immune system and deliver a payload of chemotherapy deep inside a tumour.

Nanotechnology / Nanomaterials

created Nov 09, 2010 | popularity 4.2 / 5 (6) | comments 0

Cisplatin

Cisplatin, cisplatinum, or cis-diamminedichloroplatinum(II) (CDDP) (trade names Platinol and Platinol-AQ) is a chemotherapy drug. It is used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas, and germ cell tumors. It was the first member of a class of platinum-containing anti-cancer drugs, which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA, which ultimately triggers apoptosis (programmed cell death).

For more information about Cisplatin, read the full article at Wikipedia.
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