News tagged with clinical trials
First-of-its-kind stem cell study re-grows healthy heart muscle in heart attack patients
Results from a Cedars-Sinai Heart Institute clinical trial show that treating heart attack patients with an infusion of their own heart-derived cells helps damaged hearts re-grow healthy muscle.
Medicine & Health / Cardiology
5 hours ago |
5 / 5 (3) |
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'Very promising' treatment for Huntington disease discovered
Medical researchers at the University of Alberta have discovered a promising new therapy for Huntington disease that restores lost motor skills and may delay or stop the progression of the disease based on lab model tests, ...
9 hours ago |
5 / 5 (6) |
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Many lung cancer patients get radiation therapy that may not prolong their lives
A new study has found that many older lung cancer patients get treatments that may not help them live longer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings suggest that p ...
20 hours ago |
5 / 5 (1) |
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Arthritic knees, but not hips, have robust repair response
Researchers at Duke University Medical Center used new tools they developed to analyze knees and hips and discovered that osteoarthritic knee joints are in a constant state of repair, while hip joints are not.
Feb 10, 2012 |
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Clinical trial teaches binge eaters to toss away cravings
Of 190 million obese Americans, approximately 10-15 percent engage in harmful binge eating. During single sittings, these over-eaters consume large servings of high-caloric foods. Sufferers contend with weight gain and depression ...
Feb 10, 2012 |
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First prospective clinical trial of adaptive radiotherapy for head and neck cancer patients
Researchers led by a senior investigator at Hofstra-North Shore LIJ School of Medicine and The Feinstein Institute for Medical Research have released initial findings from a first-of-a-kind clinical trial in adaptive radiotherapy ...
Feb 09, 2012 |
5 / 5 (1) |
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Short fasting cycles work as well as chemotherapy in mice
Man may not live by bread alone, but cancer in animals appears less resilient, judging by a study that found chemotherapy drugs work better when combined with cycles of short, severe fasting.
Feb 08, 2012 |
4.7 / 5 (16) |
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Study evaluates antibiotic option for treating bladder infection in women
Short-term use of the antibiotic cefpodoxime for the treatment of women with uncomplicated cystitis (bladder infection) did not meet criteria for noninferiority for achieving clinical cure compared with ciprofloxacin, a drug ...
Feb 07, 2012 |
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Risk of death from breast cancer higher among older patients
Among postmenopausal women with hormone receptor-positive breast cancer, increasing age was associated with a higher risk of death from breast cancer, according to a study in the February 8 issue of JAMA.
Feb 07, 2012 |
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Study: Rapid bone loss as possible side effect of anti-obesity drug now in clinical trials
An endocrine hormone used in clinical trials as an anti-obesity and anti-diabetes drug causes significant and rapid bone loss in mice, raising concerns about its safe use, UT Southwestern Medical Center researchers ...
Feb 07, 2012 |
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Antidepressant-suicide link in youths absent in new analysis
In 2004, concerns about antidepressant drugs increasing suicidal thoughts and behaviors in young patients prompted the FDA to issue a rare "black box warning." Now, a new analysis of clinical trial data finds that treatment ...
Medicine & Health / Psychology & Psychiatry
Feb 06, 2012 |
5 / 5 (1) |
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New drug doesn't improve disability among stroke patients
A new drug that showed promise in animal studies and an early clinical trial didn't improve disability among stroke patients, according to late-breaking research presented at the American Stroke Association's International ...
Medicine & Health / Cardiology
Feb 03, 2012 |
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Soy isoflavone supplements did not provide breast cancer protections
Soy isoflavone supplements did not decrease breast cancer cell proliferation in a randomized clinical trial, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Resear ...
Feb 03, 2012 |
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New procedure repairs severed nerves in minutes, restoring limb use in days or weeks
American scientists believe a new procedure to repair severed nerves could result in patients recovering in days or weeks, rather than months or years. The team used a cellular mechanism similar to that used by many invertebrates ...
Medicine & Health / Neuroscience
Feb 03, 2012 |
4.8 / 5 (19) |
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Rivaroxaban has less risk of brain bleeding in patients at high risk for stroke
For patients with a type of irregular heart beat called atrial fibrillation (AF), a new anti-clotting drug might be better at preventing clot-related strokes while minimizing the risk of causing a bleeding stroke. The research ...
Medicine & Health / Cardiology
Feb 02, 2012 |
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Clinical trial
In clinical trials are conducted to allow safety and efficacy data to be collected for new drugs or devices. These trials can only take place once satisfactory information has been gathered on the quality of the product and its non-clinical safety, and Health Authority/Ethics Committee approval is granted in the country where the trial is taking place.
Depending on the type of product and the stage of its development, investigators enroll healthy volunteers and/or patients into small pilot studies initially, followed by larger scale studies in patients that often compare the new product with the currently prescribed treatment. As positive safety and efficacy data are gathered, the number of patients is typically increased. Clinical trials can vary in size from a single center in one country to multicenter trials in multiple countries.
Due to the sizable cost a full series of clinical trials may incur, the burden of paying for all the necessary people and services is usually borne by the sponsor who may be the pharmaceutical or biotechnology company that developed the agent under study. Since the diversity of roles may exceed resources of the sponsor, often a clinical trial is managed by an outsourced partner such as a contract research organization
For more information about Clinical trial, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
