Related topics: cancer , vaccine
Clinical trial
hideIn clinical trials are conducted to allow safety and efficacy data to be collected for new drugs or devices. These trials can only take place once satisfactory information has been gathered on the quality of the product and its non-clinical safety, and Health Authority/Ethics Committee approval is granted in the country where the trial is taking place.
Depending on the type of product and the stage of its development, investigators enroll healthy volunteers and/or patients into small pilot studies initially, followed by larger scale studies in patients that often compare the new product with the currently prescribed treatment. As positive safety and efficacy data are gathered, the number of patients is typically increased. Clinical trials can vary in size from a single center in one country to multicenter trials in multiple countries.
Due to the sizable cost a full series of clinical trials may incur, the burden of paying for all the necessary people and services is usually borne by the sponsor who may be the pharmaceutical or biotechnology company that developed the agent under study. Since the diversity of roles may exceed resources of the sponsor, often a clinical trial is managed by an outsourced partner such as a contract research organization
For more information about Clinical trial, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
News tagged with clinical trials
Researchers say breast cancer survival improves Herceptin used with chemotherapy
Dec 12, 2009 |
not rated yet |
0
Using Herceptin with chemotherapy, instead of after, clearly improves treatment of women with HER2+ breast cancer, and should be the new standard of care, says a Mayo Clinic researcher who led what is regarded to be a key ...
Vitamin D levels associated with survival in lymphoma patients
Dec 05, 2009 |
4.7 / 5 (3) |
1
A new study has found that the amount of vitamin D in patients being treated for diffuse large B-cell lymphoma was strongly associated with cancer progression and overall survival. The results will be presented at the annual ...
Human guinea pigs link pay and risk levels
Dec 04, 2009 |
not rated yet |
0
Human guinea pigs do their homework before volunteering for high-paying clinical trials. New research shows that people equate large payments for participation in medical research with increased levels of risk. And when they ...
New study measures HIV anti-retroviral regimens' safety and efficacy
Medicine & Health / HIV & AIDS
Dec 01, 2009 |
not rated yet |
0
A study in the New England Journal of Medicine released on World AIDS Day reports that viral failure, the point at which medication can no longer suppress the HIV infection, was twice as likely and happen ...
Is it right for drug companies to carry out their own clinical trials?
Nov 30, 2009 |
not rated yet |
0
In BMJ today two experts debate whether the conflict of interest is unacceptable when drug companies carry out clinical trials on their own medicines.
First anti-seizure drug for newborns to be developed
Medicine & Health / Medications
Nov 26, 2009 |
not rated yet |
0
(PhysOrg.com) -- Researchers at the UCL Institute for Child Health are developing the first anti-seizure drug specifically for newborn babies, with the aim of reducing brain damage.
Motivational 'women-only' cardiac rehab improves symptoms of depression
Nov 17, 2009 |
not rated yet |
0
Depressive symptoms improved among women with coronary heart disease who participated in a motivationally-enhanced cardiac rehabilitation program exclusively for women, according to research presented at the American Heart ...
Viagra for women? Drug developed as antidepressant effective in treating low libido
Medicine & Health / Medications
Nov 16, 2009 |
4.4 / 5 (7) |
4
The drug flibanserin, which was originally created as an antidepressant, is effective in treating women with low libido, pooled results from three separate clinical trials have found.
Client-directed therapy technique drastically reduces divorce/separation rates
Medicine & Health / Psychology & Psychiatry
Nov 13, 2009 |
not rated yet |
0
Using four simple questions to generate client-directed feedback can greatly increase the chances that struggling couples will stay together, according to a recently published study.
New evidence that dark chocolate helps ease emotional stress
Nov 11, 2009 |
4 / 5 (4) |
2
The "chocolate cure" for emotional stress is getting new support from a clinical trial published online in ACS' Journal of Proteome Research.
Researchers mobilizing global resources to test new treatments for severe H1N1 infection
Nov 11, 2009 |
not rated yet |
0
An important, ground-breaking initiative is unfolding in the global critical care community in response to the H1N1 pandemic.
Drug shrinks lung cancer tumors in mice
Nov 10, 2009 |
4.8 / 5 (6) |
0
(PhysOrg.com) -- A potential new drug for lung cancer has eliminated tumours in 50% of mice in a new study published today in the journal Cancer Research. In the animals, the drug also stopped lung cancer ...
Stem cells restore mobility in neck-injured rats (w/ Video)
Nov 10, 2009 |
5 / 5 (9) |
1
(PhysOrg.com) -- The first human embryonic stem cell treatment approved by the FDA for human testing has been shown to restore limb function in rats with neck spinal cord injuries - a finding that could expand the clinical ...
Say yes to a clinical trial; it may be good for your health
Oct 30, 2009 |
4 / 5 (1) |
0
Patients with chronic heart failure who agree to take part in clinical trials have a better prognosis than those who do not, according to a study reported in the November European Journal of Heart Failure.(1) The finding, say th ...
Swine flu vaccine must be free and safe for high uptake
Oct 28, 2009 |
not rated yet |
0
Almost half of adults surveyed in Summer 2009 in Hong Kong (45%) say they would take up free swine flu vaccination. However, this figure drops to around 1 in 7 (15%) if the price they have to pay for the vaccine reaches $HK200 ...
