Related topics: cancer , vaccine
Clinical trial
hideIn clinical trials are conducted to allow safety and efficacy data to be collected for new drugs or devices. These trials can only take place once satisfactory information has been gathered on the quality of the product and its non-clinical safety, and Health Authority/Ethics Committee approval is granted in the country where the trial is taking place.
Depending on the type of product and the stage of its development, investigators enroll healthy volunteers and/or patients into small pilot studies initially, followed by larger scale studies in patients that often compare the new product with the currently prescribed treatment. As positive safety and efficacy data are gathered, the number of patients is typically increased. Clinical trials can vary in size from a single center in one country to multicenter trials in multiple countries.
Due to the sizable cost a full series of clinical trials may incur, the burden of paying for all the necessary people and services is usually borne by the sponsor who may be the pharmaceutical or biotechnology company that developed the agent under study. Since the diversity of roles may exceed resources of the sponsor, often a clinical trial is managed by an outsourced partner such as a contract research organization
For more information about Clinical trial, read the full article at
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News tagged with clinical trials
Stem cells restore mobility in neck-injured rats (w/ Video)
Nov 10, 2009 |
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(PhysOrg.com) -- The first human embryonic stem cell treatment approved by the FDA for human testing has been shown to restore limb function in rats with neck spinal cord injuries - a finding that could expand the clinical ...
Viagra for women? Drug developed as antidepressant effective in treating low libido
Medicine & Health / Medications
Nov 16, 2009 |
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The drug flibanserin, which was originally created as an antidepressant, is effective in treating women with low libido, pooled results from three separate clinical trials have found.
Client-directed therapy technique drastically reduces divorce/separation rates
Medicine & Health / Psychology & Psychiatry
Nov 13, 2009 |
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Using four simple questions to generate client-directed feedback can greatly increase the chances that struggling couples will stay together, according to a recently published study.
New evidence that dark chocolate helps ease emotional stress
Nov 11, 2009 |
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The "chocolate cure" for emotional stress is getting new support from a clinical trial published online in ACS' Journal of Proteome Research.
Drug shrinks lung cancer tumors in mice
Nov 10, 2009 |
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(PhysOrg.com) -- A potential new drug for lung cancer has eliminated tumours in 50% of mice in a new study published today in the journal Cancer Research. In the animals, the drug also stopped lung cancer ...
Designing drugs and their antidotes together improves patient care
Oct 04, 2009 |
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Imagine a surgical patient on a blood-thinning drug who starts bleeding more than expected, and an antidote that works immediately - because the blood thinner and antidote were designed to work together. Researchers at Duke ...
Discovery leads to rapid mouse 'personalized trials' in breast cancer
Sep 04, 2009 |
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One person's breast cancer is not the same as another person's, because the gene mutations differ in each tumor. That makes it difficult to match the best therapy with the individual patient.
Cornell makes cancer vaccine for clinical use
Aug 20, 2009 |
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The Bioproduction Facility at Cornell University has produced the first batch of NY-ESO-1 recombinant protein—a cancer vaccine—that will be used in clinical trials for patients facing either ovarian cancer or melanoma. The ...
New lab test offers better prediction of HIV microbicide safety
Medicine & Health / HIV & AIDS
Jul 10, 2009 |
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Scientists at Albert Einstein College of Medicine of Yeshiva University have devised a laboratory test for predicting whether microbicides against HIV are safe for human use. The researchers have also discovered ...
Novel therapy may prove effective in treatment of 30 percent of cancers
May 13, 2009 |
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A ground-breaking Canada-wide clinical trial led by Dr. Katherine Borden, at the Institute for Research in Immunology and Cancer (IRIC) of the Université de Montréal, has shown that a common anti-viral drug, ...
Anti-aging cosmetic reduced wrinkles in clinical trial
Apr 28, 2009 |
4 / 5 (1) |
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Scientists testing a cosmetic anti-ageing product sold on the high street have shown it can clinically reduce wrinkles and improve the appearance of skin damaged by everyday exposure to sunlight.
Male circumcision reduces HIV risk: No further evidence needed
Medicine & Health / HIV & AIDS
Apr 15, 2009 |
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Three recent African trials support male circumcision for reducing the risk of contracting HIV in heterosexual men. After including new data from these trials in their review, Cochrane Researchers have changed their previous ...
Mice and men should have more in common in clinical trials
Mar 30, 2009 |
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Just as no two humans are the same, a Purdue University scientist has shown treating mice more as individuals in laboratory testing cuts down on erroneous results and could significantly reduce the cost of ...
Hormone Relaxine helps treat heart failure: study
Mar 30, 2009 |
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Relaxine, a naturally occurring hormone that helps women adapt to pregnancy, is showing promise as a treatment for acute heart failure, a new study has found.
Alzheimer's disease therapeutic prevents long-term damage from TBI in pre-clinical studies
Mar 15, 2009 |
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A class of Alzheimer's disease drugs currently studied in clinical trials appears to reduce damage caused by traumatic brain injury in animals, researchers at Georgetown University Medical Center report in an upcoming advance ...
