News tagged with clopidogrel
Clopidogrel with aspirin doesn't prevent more small strokes, may increase risk of bleeding, death
The anti-blood clot regimen that adds the drug clopidogrel (Plavix) to aspirin treatment is unlikely to prevent recurrent strokes and may increase the risk of bleeding and death in patients with subcortical stroke according ...
Medicine & Health / Cardiology
Feb 03, 2012 |
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Drug helps maintain platelet inhibition and anti-clotting levels prior to cardiac surgery
Patients who discontinued use of an antiplatelet agent such as clopidogrel prior to undergoing cardiac surgery to lower their bleeding risk and received intravenously the platelet inhibitor cangrelor achieved a higher rate ...
Medicine & Health / Cardiology
Jan 17, 2012 |
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Allergy to Plavix can be overcome: study
Allergies to Plavix, also know by its chemical name, Clopidogrel occur in about six percent of patients given the drug, vital for the prevention of life-threatening stent thrombosis after angioplasty and percutaneous coronary ...
Medicine & Health / Medications
Jan 16, 2012 |
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Genetic test for Plavix use may be unneeded: study
A new study published Wednesday cast doubt on the usefulness of a genetic test for patients taking the anti-coagulant drug Plavix, calling into question last year's FDA warning about the blood thinner.
Medicine & Health / Medications
Dec 29, 2011 |
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Analysis does not support genetic test before use of anti-clotting drug
Although the U.S. Food and Drug Administration (FDA) has recommended that a certain type of genetic testing (for the genotype CYP2C19) be considered before prescribing the drug clopidogrel to identify individuals who may ...
Dec 27, 2011 |
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Increasing dosage of clopidogrel for patients with genetic variation improves response to medication
Among patients with stable cardiovascular disease who have a genetic variation that diminishes the response to the antiplatelet drug clopidogrel, tripling the standard daily dosage of this medication resulted in improved ...
Medicine & Health / Cardiology
Nov 16, 2011 |
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Impact of timing on carotid artery stenting after stroke or transient ischemic attack
A recent study found no significant difference in the outcome for patients who received carotid artery stenting (CAS) at more than 30 days post-transient ischemic attack (TIA) or stroke versus those who received CAS at 30 ...
Medicine & Health / Cardiology
Nov 14, 2011 |
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Results of the TRIGGER-PCI trial reported at TCT 2011
A clinical trial comparing prasugrel to clopidogrel for patients with high on-clopidogrel platelet reactivity (HCPR) following percutaneous coronary intervention (PCI) was ended early due to relatively few occurrences of ...
Medicine & Health / Cardiology
Nov 09, 2011 |
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30-day results of ADAPT-DES registry reported at TCT 2011
The relationship of platelet responsiveness to antiplatelet medications; and, the correlation of poor response, and overall platelet aggregation while on dual antiplatelet therapy to the risk of drug-eluting stent thrombosis ...
Medicine & Health / Cardiology
Nov 09, 2011 |
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World's first bedside genetic test proves effective
Tailored anti-platelet therapy, made possible through a novel point-of-care genetic test, optimizes treatment for patients who carry a common genetic variant, researchers at the University of Ottawa Heart Institute (UOHI) ...
Nov 09, 2011 |
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Researchers find gene variants that cause stent thrombosis in people with coronary artery disease
In a first-of-its-kind study, researchers from Mount Sinai School of Medicine have discovered several gene variants contributing to early stent thrombosis (ST), a devastating and often deadly complication after coronary stent ...
Oct 25, 2011 |
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TARDIS trial seeks new dimension in stroke treatment
People who suffer from acute stroke or Transient Ischaemic Attack (TIA, a mini stroke) could get better treatment in the future thanks to the expansion of a large clinical trial of a new combination of drugs led by researchers ...
Medicine & Health / Cardiology
Oct 17, 2011 |
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Increased risk of bleeding with combined use of SSRIs and antiplatelet therapy after heart attacks
Heart attack patients taking selective serotonin reuptake inhibitors (SSRIs) in combination with antiplatelet therapy -- acetylsalicylic acid (ASA), clopidogrel or both (dual antiplatelet therapy) -- are at higher risk of ...
Sep 26, 2011 |
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Study examines platelet function testing for guiding antithrombotic treatment before PCI procedures
Among patients with acute coronary syndromes undergoing a procedure such as angioplasty, those who received platelet function tests before receiving antithrombotic therapy to determine appropriate clopidogrel dosing and who ...
Sep 20, 2011 |
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Even low-dose aspirin may increase risk of GI bleeding
The risk of gastrointestinal (GI) bleeding needs to be considered when determining the potential preventive benefits associated with low-dose aspirin for cardiovascular disease and cancer. According to a new study in Clinical Ga ...
Sep 12, 2011 |
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Clopidogrel
Clopidogrel is an oral, thienopyridine class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. It is marketed by Bristol-Myers Squibb and Sanofi-Aventis under the trade name Plavix. The drug works by irreversibly inhibiting a receptor called P2Y12, an adenosine diphosphate ADP chemoreceptor. Adverse effects include hemorrhage, severe neutropenia, and thrombotic thrombocytopenic purpura (TTP).
For more information about Clopidogrel, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
