Myelotoxicity is the primary dose-limiting effect of the commonly used chemotherapeutic agent 5-fluorouracil (5-FU), which may endanger the life of the patient. Ribosome biogenesis is a key pathway regulating hematopoietic ...
Cell & Microbiology
Aug 8, 2023
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5
Quick assessment of trace blood components in untreated blood samples is possible with fluorescence tests but, in practice, blood's strong autofluorescence interferes with the analysis. In the journal Angewandte Chemie International ...
Biochemistry
May 15, 2023
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9
A research team from Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, The University of Hong Kong (HKUMed), has developed a photo-responsive nanomedicine for light-controlled colorectal cancer therapy. The ...
Bio & Medicine
Apr 21, 2022
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6
Broccoli may contain advantages beyond nutrition. A molecule found in broccoli, cabbage and more digests down into DIM, a compound with brighter benefits than the name implies, such as inducing cell death in breast, prostate ...
Cell & Microbiology
Jan 24, 2022
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194
Epithelial cells are held together and connected by several different types of structures that form cell-cell contacts. One of these structures, found near the top surface of the cell, is the adherens junction. This junction ...
Molecular & Computational biology
May 8, 2020
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86
Humans have around 400 "smell-sensing" genes which activate in a combination of ways to allow us to smell the ranges of smells that we do. However, the genes have been found to be expressed in parts of the body other than ...
Biotechnology
Mar 12, 2020
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79
A group of scientists from NUST MISIS has presented the test results of an innovative oncotherapy technology based on hyperthermia—heating nanoparticles that have been introduced into a tumour to kill it. A drug based on ...
Bio & Medicine
Mar 12, 2020
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32
In almost all cases of colon cancer, a specific gene is mutated—this offers opportunities to develop broadly effective therapeutic approaches. Research teams in Würzburg have taken this a step further.
Cell & Microbiology
Nov 5, 2019
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8
Onions, cabbage, garlic. While nutritious, eating these foods can lead to an embarrassing side effect: smelly flatulence. More than just smelly, hydrogen sulfide, the chemical compound responsible for the rotten-egg aroma, ...
Biochemistry
Oct 7, 2019
0
109
Many cells, including cancer cells, are known to secrete short RNAs in tiny vesicles, which then move inside other cells—potentially a form of cell-to-cell communication.
Cell & Microbiology
Oct 29, 2018
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