News tagged with coupled receptor
Study Unravels Detail of 'Most Important' Cellular Signal
Dec 03, 2009 |
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(PhysOrg.com) -- A new study provides crucial details that promise to help researchers better understand, and perhaps fine-tune with drugs, one of the most important signaling mechanisms in human cells, according to a study ...
Beginning to see the light
Sep 29, 2008 |
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(PhysOrg.com) -- Scientists have detailed the active form of a protein which they hope will enhance our understanding of the molecular mechanisms of vision, and advance drug design.
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Many receptor models used in drug design may not be useful after all
Oct 02, 2008 |
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It may very well be that models used for the design of new drugs have to be regarded as impractical. This is the sobering though important conclusion of the work of two Leiden University scientists published in Science this w ...
Scripps Research scientists define structure of important neurological receptor
Oct 06, 2008 |
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Scientists from The Scripps Research Institute have determined the structure of an adenosine receptor that plays a critical role in a number of important physiological processes including pain, breathing, ...
New approach for growing bone
Oct 07, 2009 |
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The natural cycle of building bone to maintain skeletal strength and then breaking it down for the body's calcium needs is delicately balanced, but diseases like osteoporosis break down too much bone without adequate bone ...
Looking beyond the drug receptor for clues to drug effectiveness
Aug 25, 2008 |
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Antipsychotic drugs that are widely used to treat schizophrenia and other problems may not work as scientists have assumed, according to findings from Duke University Medical Center researchers that could lead to changes ...
Nicotine may have more profound impact than previously thought
Apr 03, 2009 |
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Nicotine isn't just addictive. It may also interfere with dozens of cellular interactions in the body, new Brown University research suggests.
Biology of flushing could renew niacin as cholesterol drug
Apr 06, 2009 |
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Deft molecular detective work at Duke University Medical Center suggests that scientists may soon be able to resurrect niacin as one of the best and cheapest ways to manage cholesterol.
Bioelectronics: Progress toward drug screening with a cell–transistor biosensor
Jun 25, 2007 |
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To develop selective measurement techniques for diagnostics, drug research, and the detection of poisons, researchers would like to combine the high specificity of biochemical reactors with universal microelectronics.
Discovery of 'overdrive' protein could broaden drug design options
Biology /
Feb 12, 2008 |
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New research by scientists at the University of North Carolina at Chapel Hill shows for the first time that an important family of proteins known to function at the cell surface also functions at a site within the cell.
Variants of 'umami' taste receptor contribute to our individualized flavor worlds
Jul 08, 2009 |
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Using a combination of sensory, genetic, and in vitro approaches, researchers from the Monell Center confirm that the T1R1-T1R3 taste receptor plays a role in human umami (amino acid) taste.
Predicting the future in ovarian cancer
Nov 15, 2007 |
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Kisspeptin and its receptor GPR54 predict a favourable clinical outcome in women with ovarian carcinoma, and are specific for the clear cell carcinoma subtype, research published this week in the online open access journal, ...
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