News tagged with crohn s disease

Could a probiotic be used to treat inflammatory bowel disease?

Scientists have been unclear for some time about how most probiotics work. A new study has found a scientific 'design' for a probiotic that could be used to treat inflammatory bowel disease (IBD), such as Crohn's disease.

Medicine & Health / Research

created Oct 20, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Genetic study sheds new light on auto-immune arthritis

The team of researchers from the Universities of Bristol, Queensland. Oxford, Texas and Toronto, used a technique called genome-wide association where millions of genetic markers are measured in thousands of people that have ...

Medicine & Health / Genetics

created Jul 10, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

MR enterography as effective as CT in diagnosing Crohn's disease, reduces radiation exposure

A new study from Rhode Island Hospital has found that MR enterography (MRE) without the use of an anti-peristaltic agent were as reliable as CT enterography (CTE) in determining the presence of Crohn's disease. Additionally, ...

Medicine & Health / Other

created Jun 15, 2011 | popularity not rated yet | comments 0

Researchers pinpoint role of key proteins in Crohn's Disease

(Medical Xpress) -- Researchers at the University of Toronto have discovered the role the interactions between key proteins plays in the body’s response to Crohn’s Disease - a revelation that may lead to the development ...

Medicine & Health / Research

created Jun 14, 2011 | popularity 4.5 / 5 (4) | comments 0 | with audio podcast

Protein from probiotic bacteria may alleviate inflammatory bowel disorders

A protein isolated from beneficial bacteria found in yogurt and dairy products could offer a new, oral therapeutic option for inflammatory bowel disorders (IBD), suggests a study led by Vanderbilt University Medical Center ...

Medicine & Health / Research

created May 23, 2011 | popularity not rated yet | comments 0 | with audio podcast

Use of naltrexone reduces inflammation in Crohn's patients

Naltrexone reduced inflammation in Crohn's patients in a research study at Penn State College of Medicine.

Medicine & Health / Diseases

created May 19, 2011 | popularity not rated yet | comments 0 | with audio podcast

Duplicating immunity boosting regulatory T-cells to unprecedented levels

University of Minnesota Medical School researchers have discovered a method to quickly and exponentially grow regulatory T-cells – also known as "suppressor cells." The new process enables replication of the cells by ...

Medicine & Health / Research

created May 18, 2011 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Adalimumab levels detected in cord blood and infants exposed in utero

Adalimumab (ADA), a drug often prescribed for women with Crohn's disease, actively crosses the placenta during the final trimester of pregnancy and remains in a newborn's bloodstream for at least three months, researchers ...

Medicine & Health / Medications

created May 08, 2011 | popularity not rated yet | comments 0

C. difficile increases risk of death 6-fold in patients with inflammatory bowel disease

Patients admitted to hospital with inflammatory bowel disease (IBD) face a sixfold greater risk of death if they become infected with Clostridium difficile, a new study has found. The researchers say IBD patients should be scr ...

Medicine & Health / Diseases

created Apr 20, 2011 | popularity 4 / 5 (1) | comments 1

Clinical trial success for Crohn's disease cell therapy

Speaking at the UK National Stem Cell Network annual science meeting later today, Professor Miguel Forte will describe research into a new cell therapy for chronic inflammatory conditions such as Crohn's disease. Patient's ...

Medicine & Health / Diseases

created Mar 31, 2011 | popularity not rated yet | comments 0

Common parasite uncovers key cause of Crohn's

(PhysOrg.com) -- Immune systems have their sinister side, especially when they have not learned how hard to fight. Crohn's disease and other inflammatory bowel diseases inflict more than a million Americans ...

Medicine & Health / Research

created Feb 23, 2011 | popularity 4.7 / 5 (22) | comments 12 | with audio podcast

Celiac disease and Crohn's disease share part of their genetic background

An investigation has found that celiac disease and Crohn's disease, both inflammatory diseases of the gastrointestinal tract, share at least four genetic risk loci. Together, researchers from the University of Groningen, ...

Medicine & Health / Genetics

created Jan 27, 2011 | popularity not rated yet | comments 0

Researchers find vitamin D absorption is diminished in patients with Crohn's disease

Researchers from Boston University School of Medicine (BUSM) have for the first time shown that reduced vitamin D absorption in patients with quiescent Crohn's disease (CD) may be the cause for their increased risk for vitamin ...

Medicine & Health / Diseases

created Jan 18, 2011 | popularity 5 / 5 (1) | comments 0

The heritability of Crohn's disease better understood

A University of Liege GIGA-Research Unit team has discovered new particular genetic mutations which influence hereditary predisposition to Crohn's disease, a chronic inflammatory disease of the bowel. The rare variants discovered ...

Medicine & Health / Genetics

created Dec 17, 2010 | popularity 5 / 5 (2) | comments 1

Inflammatory bowel disease causes post traumatic stress, say doctors

The inflammatory bowel disorder Crohn's disease produces its own variant of post traumatic stress (PTSD), indicates research published online in Frontline Gastroenterology.

Medicine & Health / Diseases

created Dec 01, 2010 | popularity 4.5 / 5 (2) | comments 0

Crohn's disease

Crohn's disease (also known as granulomatous colitis and regional enteritis) is an inflammatory disease of the intestines that may affect any part of the gastrointestinal tract from anus to mouth, causing a wide variety of symptoms. It primarily causes abdominal pain, diarrhea (which may be bloody), vomiting, or weight loss, but may also cause complications outside of the gastrointestinal tract such as skin rashes, arthritis and inflammation of the eye.

Crohn's disease is an autoimmune disease, in which the body's immune system attacks the gastrointestinal tract, causing inflammation; it is classified as a type of inflammatory bowel disease. There has been evidence of a genetic link to Crohn's disease, putting individuals with siblings afflicted with the disease at higher risk. It is understood to have a large environmental component as evidenced by the higher number of cases in western industrialized nations. Males and females are equally affected. Smokers are three times more likely to develop Crohn's disease. Crohn's disease affects between 400,000 and 600,000 people in North America. Prevalence estimates for Northern Europe have ranged from 27–48 per 100,000. Crohn's disease tends to present initially in the teens and twenties, with another peak incidence in the fifties to seventies, although the disease can occur at any age.

There is no known pharmaceutical or surgical cure for Crohn's disease. Treatment options are restricted to controlling symptoms, maintaining remission and preventing relapse.

The disease was independently described in 1904 by Polish surgeon Antoni Leśniowski and in 1932 by American gastroenterologist Burrill Bernard Crohn, for whom the disease was named. Crohn, along with two colleagues, described a series of patients with inflammation of the terminal ileum, the area most commonly affected by the illness. For this reason, the disease has also been called regional ileitis or regional enteritis.

For more information about Crohn's disease, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: inflammatory bowel disease