How highly resistant strains of fungi emerge

An international research team has deciphered the mechanism by which the fungus Cryptococcus neoformans is resistant to fungus-specific drugs. It is a yeast-like fungus that can infect humans. Specific drugs, named antifungals, ...

The invisibility cloak of a fungus

While viruses and bacteria regularly manage to infect the human organism, fungi only very rarely succeed. The reason for this is that the human immune system can recognize them very easily because their cells are surrounded ...

'Living fossil' may upend basic tenet of evolutionary theory

The field of evolutionary biology has seen its share of spirited debates. But if there's one principle that virtually every expert in the field agrees on, it's that natural selection occurs at the level of the genome.

Deadly fungus uses unexpected system to control its virulence

A research team led by UC San Francisco scientists has discovered a cellular signaling system that regulates the virulence of Cryptococcus neoformans, a fungus that has been estimated to cause nearly a million cases of meningitis ...

Deadly human pathogen Cryptococcus fully sequenced

Within each strand of DNA lies the blueprint for building an organism, along with the keys to its evolution and survival. These genetic instructions can give valuable insight into why pathogens like Cryptococcus neoformans—a ...

Sudy unravel mechanism critical for fungal virulence

Metallothioneins, proteins able to capture metal ions, play a major role in the virulence of Cryptococcus neoformans, a fungal pathogen which causes severe infections in immunodeficient and immunocompetent individuals (AIDS ...

New study finds titan cells protect Cryptococcus

Giant cells called "titan cells" protect the fungus Cryptococcus neoformans during infection, according to two University of Minnesota researchers. Kirsten Nielsen, Ph.D., an assistant professor in the department of microbiology, ...

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