News tagged with cyclooxygenase

Cyclooxygenase

Cyclooxygenase (COX) is an enzyme (EC 1.14.99.1) that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane. Pharmacological inhibition of COX can provide relief from the symptoms of inflammation and pain. Non-steroidal anti-inflammatory drugs, such as aspirin and ibuprofen, exert their effects through inhibition of COX. The names "prostaglandin synthase (PHS)" and "prostaglandin endoperoxide synthetase (PES)" are still used to refer to COX.

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New research discovers key to survival of brain cells

Nicolas G. Bazan, MD, Ph.D, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health Sciences Center New Orleans, and David Stark, an MD/Ph.D student working in his lab, have discovered how a key ...

Medicine & Health / Neuroscience

created Sep 28, 2011 | popularity not rated yet | comments 0

Common anti-inflammatory coaxes liver cancer cells to commit suicide

The anti-inflammatory drug celecoxib, known by the brand name Celebrex, triggers liver cancer cell death by reacting with a protein in a way that makes those cells commit suicide, according to a new study.

Medicine & Health / Cancer

created May 16, 2011 | popularity 4.3 / 5 (6) | comments 0 | with audio podcast

NSAID receptor responsible for olive oil's 'cough' and more

Scientists from the Monell Center and collaborators report that a receptor known as TRPA1 is activated by two structurally unrelated anti-inflammatory compounds. The first, oleocanthal, is a natural polyphenolic anti-inflammatory ...

Medicine & Health / Neuroscience

created Jan 18, 2011 | popularity 4.5 / 5 (4) | comments 0

Fluorescent compounds make tumors glow

A series of novel imaging agents could light up tumors as they begin to form - before they turn deadly - and signal their transition to aggressive cancers.

Medicine & Health / Cancer

created Apr 29, 2010 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Researchers detail how aging undermines bone healing

Researchers have unraveled crucial details of how aging causes broken bones to heal slowly, or not at all, according to study results published today in the Journal of Bone and Mineral Research. The research team also succes ...

Medicine & Health / Research

created Jan 15, 2009 | popularity 4.6 / 5 (5) | comments 0

Organometallic compounds as new drugs? Cobalt-containing aspirin complex with potential anti-tumor properties

Despite considerable progress in modern chemotherapy, there remains a large demand for innovative anti-tumor agents. A new approach involves modeling the pharmacological properties of established drugs with organometallic ...

Chemistry /

created Jan 13, 2009 | popularity 2.8 / 5 (6) | comments 0