News tagged with demethylation
Genetic changes outside nuclear DNA suspected to trigger more than half of all cancers
Mar 24, 2009 |
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A buildup of chemical bonds on certain cancer-promoting genes, a process known as hypermethylation, is widely known to render cells cancerous by disrupting biological brakes on runaway growth. Now, Johns Hopkins scientists ...
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Growth of new brain cells requires 'epigenetic' switch
Jan 08, 2009 |
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New cells are born every day in the brain's hippocampus, but what controls this birth has remained a mystery. Reporting in the January 1 issue of Science, neuroscientists at the Johns Hopkins University School of Medicine have d ...
Newly found enzymes may play early role in cancer
Dec 24, 2008 |
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Researchers have discovered two enzymes that, when combined, could be involved in the earliest stages of cancer. Manipulating these enzymes genetically might lead to targeted therapies aimed at slowing or preventing the onset ...
Study shows immune system protein involved in reprogramming adult cells to express stem cell genes
24 minutes ago |
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(PhysOrg.com) -- Scientists have discovered a protein required to quickly and efficiently reprogram human skin cells to express embryonic stem cell genes.
Scientists discover novel histone demethylase protein complex
Biology /
Dec 05, 2008 |
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The Stowers Institute's Workman Lab has discovered a novel histone demethylase protein complex characterized in work published today in Molecular Cell.
Researchers reveal structure of protein that repairs damage to cancer cells
Biology /
Apr 23, 2008 |
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A team of University of Chicago scientists has shown how two proteins locate and repair damaged genetic material inside cells.
A miR boost enables acute leukemia cells to mature
Apr 03, 2009 |
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A new study by Ohio State University cancer researchers shows that boosting the level of a molecule called miR-29b in acute myeloid leukemia (AML) cells can reverse gene changes that trap the cells in an immature, ...
Study finds genomic changes in the brains of people who commit suicide
Oct 23, 2008 |
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Are genes destiny? Alternatively, are we simply the products of our environment? There is a growing sense that neither of these two possibilities fully captures the essence of the risk for psychiatric disorders. New light ...
New revelations in epigenetic control shed light on breast cancer
Mar 05, 2008 |
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Epigenetic regulation – modifications to the structure of chromatin that influence which genes are expressed in a cell – is a key player in embryonic development and cancer formation. Researchers at the European Molecular ...
Study finds 231 new genes associated with head and neck cancer
Oct 04, 2009 |
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A Henry Ford Hospital study has identified 231 new genes associated with head and neck cancer, one of the most deadly cancers responsible for 2.1 percent of all cancer deaths in the United States.
Pushmi-pullyu of B-cell development discovered
Jun 25, 2009 |
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James Hagman, Ph.D., professor of immunology at National Jewish Health and his colleagues have identified two "molecular motors" that work in opposing directions to control the development of B cells in the immune system.
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