Molecular modelling to help create better, safer drugs

(Phys.org) —How our bodies break down the common drugs ibuprofen, diclofenac and warfarin is the subject of a new study from the University of Bristol, published in the Journal of the American Chemical Society. The research ...

Vultures dying at alarming rate

Vultures in South Asia were on the brink of extinction until Lindsay Oaks and Richard Watson, from The Peregrine Fund in the US, undertook observational and forensic studies to find out why the number of birds was falling ...

Rapid test to save Indian vultures from extinction

Vulture population declined at a catastrophic rate on the Indian subcontinent over the past 15 years. In 2004 scientists identified the cause: the drug Diclofenac. Meanwhile the use of this anti-inflammatory agent in veterinary ...

Diclofenac

Diclofenac (marketed under many brand names, see below: Trade names) is a non-steroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

The name is derived from its chemical name: 2-(2,6-dichloranilino) phenylacetic acid.

In the United Kingdom, India, Brazil and the United States, it may be supplied as either the sodium or potassium salt, in China most often as the sodium salt, while in some other countries only as the potassium salt. Diclofenac is available as a generic drug in a number of formulations. Over-the-counter (OTC) use is approved in some countries for minor aches and pains and fever associated with common infections.

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