Scientists reveal hidden structures in bacterial DNA

DNA contains the instructions for life, encoded within genes. Within all cells, DNA is organised into very long lengths known as chromosomes. In animal and plant cells these are double-ended, like pieces of string or shoelaces, ...

SMiLE-seq: A new technique speeds up genetics

Scientists at EPFL have developed a technique that can be a game-changer for genetics by making the characterization of DNA-binding proteins much faster, more accurate, and efficient.

Scientists publish the first RNA interactome of the human nucleus

Studying sequence and function of DNA has been in the focus of life sciences for decades, but now the interest of many researchers has turned to the RNA. Today, many scientists believe that RNA molecules, together with a ...

A new way of fighting bacteria?

In bacteria, toxin-antitoxin systems consist of a set of two closely linked genes. Situated on the same chromosome, they encode both a protein 'poison' and a counteracting 'antidote'. Under normal conditions, the antitoxin ...

DNA division can slow to a halt

A key mystery of the DNA replication process has been unraveled by researchers from King Abdullah University of Science and Technology (KAUST).

Faster, not stronger: How a protein regulates gene expression

Inside the cell, DNA is tightly coiled and packed with several proteins into a structure called "chromatin", which allows DNA to fit in the cell while also preventing genes from being expressed at the wrong time. Guided by ...

Versatility in genetic expression aids rapid microbial evolution

Microbiologists from Trinity College Dublin have discovered that an identical protein is used differently by two species of bacteria to help them cope with distinct types of environmental stress. The discovery reveals an ...

Cell memory mechanism discovered

The cells in our bodies can divide as often as once every 24 hours, creating a new, identical copy. DNA binding proteins called transcription factors are required for maintaining cell identity. They ensure that daughter cells ...

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