News tagged with dna modification
Ancient DNA holds clues to climate change adaptation
(PhysOrg.com) -- Thirty-thousand-year-old bison bones discovered in permafrost at a Canadian goldmine are helping scientists unravel the mystery about how animals adapt to rapid environmental change.
Jan 31, 2012 |
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Unique genetic marker may improve detection of recurrent ovarian cancer
Ovarian cancer is a major health concern for women and the identification of sensitive biomarkers for early detection and/or monitoring of disease recurrence is of high clinical relevance.
Dec 07, 2011 |
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Study identifies mechanisms cells use to remove bits of RNA from DNA strands
When RNA component units called ribonucleotides become embedded in genomic DNA, which contains the complete genetic data for an organism, they can cause problems for cells. It is known that ribonucleotides ...
Dec 04, 2011 |
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Patterns of new DNA letter in brain suggest distinct function
In 2009, the DNA alphabet expanded. Scientists discovered that an extra letter or "sixth nucleotide" was surprisingly abundant in DNA from stem cells and brain cells.
Medicine & Health / Neuroscience
Oct 30, 2011 |
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Scientists discover 'fickle' DNA changes in brain
Johns Hopkins scientists investigating chemical modifications across the genomes of adult mice have discovered that DNA modifications in non-dividing brain cells, thought to be inherently stable, instead underwent large-scale ...
Medicine & Health / Neuroscience
Sep 30, 2011 |
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Scientists complete first mapping of molecule found in human embryonic stem cells
Stem cell researchers at UCLA have generated the first genome-wide mapping of a DNA modification called 5-hydroxymethylcytosine (5hmC) in embryonic stem cells, and discovered that it is predominantly found in genes that are ...
Jul 21, 2011 |
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Mayo Clinic reports new findings on noninvasive test for pancreatic cancer
Pancreatic cancer has one of the highest mortality rates of any of the major cancers, and of the 43,000-plus Americans diagnosed with the disease each year, more than 94 percent die within five years of diagnosis. One reason ...
May 11, 2011 |
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Epigenetic study reveals new insights into breast cancer
The most comprehensive analysis yet of the epigenetic modifications present in breast cancer has revealed potentially important new ways to detect and treat the disease, Belgian researchers have reported.
May 05, 2011 |
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DNA repair protein caught in act of molecular theft
Scientists have observed, for the first time, an intermediate stage in the chemical process that repairs DNA methylation damage and regulates many important biological functions that impact health conditions ...
Nov 10, 2010 |
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Select agents should be defined by DNA sequence in today's era of synthetic biology
A DNA sequence-based system to better define when a pathogen or toxin is subject to Select Agent regulations could be developed, says a new report from the National Research Council, which adds that this could be coupled ...
Aug 03, 2010 |
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Scientists discover how 'companion' cells to sperm protect them from genetic damage
In plant pollen grains, sperm cells, which carry the genetic material to be passed on to progeny, are cocooned within larger "companion" cells that are called pollen vegetative cells. These companions provide sperm with ...
Biology /
Feb 05, 2009 |
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Gene switch sites found mainly on 'shores,' not just 'islands' of the human genome
Scientists who study how human chemistry can permanently turn off genes have typically focused on small islands of DNA believed to contain most of the chemical alterations involved in those switches. But after an epic tour ...
Jan 18, 2009 |
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Rethinking the Genetic Theory of Inheritance
Scientists at the Centre for Addiction and Mental Health (CAMH) have detected evidence that DNA may not be the only carrier of heritable information; a secondary molecular mechanism called epigenetics may also account for ...
Jan 18, 2009 |
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In lung cancer, silencing one crucial gene disrupts normal functioning of genome
While examining patterns of DNA modification in lung cancer, a team of international researchers has discovered what they say is a surprising new mechanism. They say that "silencing" of a single gene in lung cancer led to ...
Dec 31, 2008 |
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