News tagged with dna synthesis
Visualization of DNA synthesis in vivo
Researchers of the University of Zurich have discovered a new substance for labeling and visualization of DNA synthesis in whole animals. Applications for this technique include identifying the sites of virus ...
Dec 13, 2011 |
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Human skin begins tanning in seconds, and here's how
We all know that human skin tans after days spent in the sun. That relatively slow process has known links to ultraviolet (and specifically UVB) exposure, which leads to tanning only after it damages the DNA of skin cells. ...
Nov 03, 2011 |
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Structure of a molecular copy machine: How mitochondrial genes are transcribed
Mitochondria are compartments within cells and have their own DNA. The key protein required for the expression of the genetic information in this DNA is the mitochondrial RNA polymerase enzyme. Its three-dimensional structure ...
Sep 26, 2011 |
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Newly identified DNA repair defect linked to increased risk of leukemia relapse
A newly identified defect in a DNA repair system might leave some young leukemia patients less likely to benefit from a key chemotherapy drug, possibly putting them at greater risk of relapse. The problem was identified in ...
Sep 26, 2011 |
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Peptides for fighting ovarian cancer developed
A team of German and Italian EU-funded scientists has designed peptides that can target the protein-protein interface of an enzyme that plays a key part in the DNA synthesis crucial for cancer growth.
Aug 08, 2011 |
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Low dose naltrexone (LDN): Harnessing the body's own chemistry to treat human ovarian cancer
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that a low dose of the opioid antagonist naltrexone (LDN) has an extraordinarily potent antitumor effect on human ...
Jul 12, 2011 |
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Discovery of DNA silencing mechanism reveals how plants protect their genome
(PhysOrg.com) -- Researchers at the RIKEN Plant Science Center (PSC) have clarified a key epigenetic mechanism by which an enzyme in the model plant Arabidopsis protects cells from harmful DNA elements. Published ...
May 12, 2011 |
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Researchers demonstrate why DNA breaks down in cancer cells
Damage to normal DNA is a hallmark of cancer cells. Although it had previously been known that damage to normal cells is caused by stress to their DNA replication when cancerous cells invade, the molecular basis for this ...
May 03, 2011 |
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Open-source software designed to minimize synthetic biology risks
A software package designed to minimize the potential risks of synthetic biology for the nation's defense and security is now available to the gene synthesis industry and synthetic biology community in an open-source format.
Mar 21, 2011 |
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Answers to a rare and tragic form of epilepsy
A new study offers critical insight into the biochemistry of a rare and fatal form of epilepsy known as Lafora disease, a genetic condition that typically strikes children in their teens. The disease is characterized ...
Mar 01, 2011 |
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Stop and go: How the cell deals with transcriptional roadblocks
Gene transcription is central to cell function, as it converts the information stored in the DNA into RNA molecules of defined sequence, which then program protein synthesis. The enzyme RNA polymerase II (Pol II) is responsible ...
Feb 23, 2011 |
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Method of DNA repair linked to higher likelihood of genetic mutation
Accurate transmission of genetic information requires the precise replication of DNA. Errors in DNA replication are common and nature has developed several cellular mechanisms for repairing these mistakes. ...
Feb 15, 2011 |
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Paving the way for new single-molecule electrochemical switches
The degree of twisting of natural helical structures, such as the DNA double-helix, plays an essential role in many important biological functions. Because of their twisted architecture, artificial helices ...
Jan 21, 2011 |
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Select agents should be defined by DNA sequence in today's era of synthetic biology
A DNA sequence-based system to better define when a pathogen or toxin is subject to Select Agent regulations could be developed, says a new report from the National Research Council, which adds that this could be coupled ...
Aug 03, 2010 |
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iGEM team helps prevent rogue use of synthetic biology
A team of students from ENSIMAG, an engineering school in Grenoble, France, and Virginia Tech is using bioinformatics to implement federal guidance on synthetic genomics. The students' work will help gene synthesis companies ...
Jul 19, 2010 |
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