News tagged with dna targets
Researchers increase understanding of gene's potentially protective role in Parkinson's
Treatments for Parkinson's disease, estimated to affect 1 million Americans, have yet to prove effective in slowing the progression of the debilitating disease.
Medicine & Health / Neuroscience
Feb 07, 2012 |
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Three is the magic number: A chain reaction required to prevent tumor formation
Protein p53 is known for controlling the life and death of a cell and has a key role in cancer research. P53 is known to be inactive in 50 percent of cancer patients. If researchers succeed in re-establishing the presence ...
Jan 20, 2012 |
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Researchers validate preclinical effectiveness of TB drug target
In research at SRI International, scientists evaluating new drug targets against tuberculosis (TB) recently validated the preclinical effectiveness of a target that could rapidly eliminate infections and potentially shorten ...
Nov 29, 2011 |
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New potential therapeutic target identified for Diffuse Large B-Cell Lymphoma
Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have discovered a new potential therapeutic target for Diffuse Large B-Cell Lymphoma (DLBCL), the most aggressive and ...
Nov 28, 2011 |
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Study identifies a key molecular switch for telomere extension by telomerase
Researchers at the University of Illinois at Chicago College of Medicine describe for the first time a key target of DNA damage checkpoint enzymes that must be chemically modified to enable stable maintenance of chromosome ...
Nov 23, 2011 |
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Tamoxifen resistance -- and how to defeat it
In the last three decades, thousands of women with breast cancer have taken the drug tamoxifen, only to discover that the therapy doesn't work, either because their tumors do not respond to the treatment at all, or because ...
Nov 13, 2011 |
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Bacteria shed light on new drug targets for inherited cancers
Cancer Research UK scientists have succeeded in purifying a protein found in bacteria that could reveal new drug targets for inherited breast and ovarian cancers - and other cancers linked to DNA repair faults. The study ...
Sep 06, 2011 |
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Researchers discover possible drug targets for common non-Hodgkin's lymphoma
Researchers at the University of Maryland School of Medicine have discovered a novel interaction between two proteins involved in regulating cell growth that could provide possible new drug targets for treating diffuse large ...
Jul 19, 2011 |
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Team perfects non-lethal way of switching off essential genes in mice
One way of discovering a gene's function is to switch it off and observe how the loss of its activity affects an organism. If a gene is essential for survival, however, then switching it off permanently will ...
Apr 14, 2011 |
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Promising new 'antigene' therapy
Antigene therapy is a promising new treatment strategy that uses a DNA-based drug to pinpoint light energy to a target gene shutting down its activity. A review article published online ahead of print in Oligonucleotides, a peer ...
Oct 21, 2010 |
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MicroRNA to combat cancer
(PhysOrg.com) -- Researchers from the Queensland Institute of Medical Research, the Garvan Institute of Medical Research and the University of California-San Francisco have found a new way to kill cancer cells, opening the ...
Sep 28, 2010 |
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Yeast unravels effects of chemotherapy drugs
Until now, the mode of action of nitrogen-containing bisphosphonate (N-BP) cancer drugs, used to relieve bone pain and to prevent skeletal complications in bone metastasis, has been almost entirely unknown. Researchers writing ...
Sep 09, 2009 |
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Cancer cells need normal, nonmutated genes to survive
Corrupt lifestyles and vices go hand in hand; each feeds the other. But even the worst miscreant needs customary societal amenities to get by. It's the same with cancer cells. While they rely on vices in the form of genetic ...
May 28, 2009 |
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Moving gene therapy forward with mobile DNA
Gene therapy is the introduction of genetic material into a patient's cells resulting in a cure or a therapeutic effect. In recent years, it has been shown that gene therapy is a promising technology to treat or even cure ...
May 03, 2009 |
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Scientists identify key component in cell replication
Last week, a presidential limousine shuttled Barack Obama to the most important job in his life. Scientists at the Stanford University School of Medicine have now identified a protein that does much the same for the telomerase ...
Jan 29, 2009 |
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