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Double helix

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In geometry a double helix (plural helices) typically consists of two congruent helices with the same axis, differing by a translation along the axis, which may or may not be half-way.

The term "double helix" is commonly encountered in molecular biology, where it refers to the structure of DNA. The double-helix model of DNA structure was first published in the journal Nature by James D. Watson and Francis Crick in 1953, based upon the crucial X-ray diffraction image of DNA (labeled as "Photo 51") from Rosalind Franklin in 1952 , followed by her more clarified DNA image with Raymond Gosling, Maurice Wilkins, Alexander Stokes and Herbert Wilson, as well as base-pairing chemical and biochemical information by Erwin Chargaff.

Crick, Wilkins and Watson each received one third of the 1962 Nobel Prize in Physiology or Medicine for their contributions to the discovery. (Franklin, whose breakthrough X-ray diffraction data was used to formulate the DNA structure, died in 1958, and thus was ineligible to be nominated for a Nobel Prize.)

The DNA double helix is a right-handed spiral polymer of nucleic acids, held together by nucleotides which base pair together. A single turn of the helix constitutes ten nucleotides. The double helix structure of DNA contains a major groove and minor groove, the major groove being wider than the minor groove. Given the difference in widths of the major groove and minor groove, many proteins which bind to DNA do so through the wider major groove .

The order, or sequence, of the nucleotides in the double helix within a gene specifies the primary structure of a protein.

The term entered popular culture with the publication in 1968 of The Double Helix: A Personal Account of the Discovery of the Structure of DNA, by James Watson.

For more information about Double helix, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.


News tagged with double helix


Understanding DNA Repair and Cancer

Biology / Cell & Microbiology

created Dec 03, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- A protein that plays a key role in copying DNA also plays a vital role in repairing breaks in it, UC Davis scientists have found. The work is helping researchers understand how cancer cells can resist radiation ...





Search results for double helix


Grooving Down the Helix

Grooving down the helix: Researchers show how proteins slide along DNA to carry out vital biological processes

Biology / Biotechnology

created Dec 03, 2009 | popularity 4 / 5 (3) | comments 0

(PhysOrg.com) -- A team of scientists has made a major step in understanding how molecules locate the genetic information in DNA that is necessary to carry out important biological processes.


Molecular freight: Synthetic nanoscale transport system modeled on nature

Chemistry / Biochemistry

created Dec 21, 2009 | popularity 5 / 5 (3) | comments 0

(PhysOrg.com) -- Just like our roads, there is a lot of traffic within the cells in our bodies, because cell components, messenger molecules, and enzymes must also be brought to the right places in the cell. One of these ...


Hot electron solar cell

Hot Electrons Could Double Solar Cell Power Efficiency

Nanotechnology / Nanophysics

created Dec 18, 2009 | popularity 4.2 / 5 (13) | comments 2

Scientists have experimentally verified a theory suggesting that hot electrons could double the output of solar cells. The researchers, from Boston College, have built solar cells that successfully use hot ...


New management methods extend blackberry season

New management methods extend blackberry season

Biology / Ecology

created Dec 11, 2009 | popularity not rated yet | comments 0

Fruit growers' profits have traditionally been limited by the seasons, particularly in colder climates where growing seasons can be short. Thanks to researchers and fruit breeders, newly developed varieties ...


Scientists reveal key structure from ebola virus

Medicine & Health / Research

created Dec 08, 2009 | popularity 5 / 5 (2) | comments 0

Scientists at The Scripps Research Institute have determined the structure of a critical protein from the Ebola virus, which, though rare, is one of the deadliest viruses on the planet killing between 50 and 90 percent of ...


New molecule identified in DNA damage response

New molecule identified in DNA damage response

Biology / Cell & Microbiology

created Dec 08, 2009 | popularity 5 / 5 (2) | comments 0

(PhysOrg.com) -- Evolution places the highest premium on reproduction, natural selection’s only standard for biological success. In the case of replicating cells, life spares no expense to ensure that the ...


A little magic provides an atomic-level look at bone

Chemistry / Analytical Chemistry

created Dec 02, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- A new study using solid-state NMR spectroscopy to analyze intact bone paves the way for atomic-level explorations of how disease and aging affect bone. The research by scientists at the University of Michigan ...


Switchable Nanostructures Made with DNA

Switchable Nanostructures Made with DNA

Nanotechnology / Bio & Medicine

created Dec 21, 2009 | popularity 4.8 / 5 (8) | comments 0

(PhysOrg.com) -- Scientists at the U.S. Department of Energy’s Brookhaven National Laboratory have found a new way to use a synthetic form of DNA to control the assembly of nanoparticles — this time resulting ...


Diabetes cases to double and costs to triple by 2034

Medicine & Health / Diseases

created Nov 27, 2009 | popularity not rated yet | comments 0

In the next 25 years, the number of Americans living with diabetes will nearly double, increasing from 23.7 million in 2009 to 44.1 million in 2034. Over the same period, spending on diabetes will almost triple, rising from ...


Research shows some plants can remove indoor pollutants

Research shows some plants can remove indoor pollutants

Biology / Plants & Animals

created Dec 02, 2009 | popularity 4.8 / 5 (18) | comments 3

(PhysOrg.com) -- Some plants have the ability to drastically reduce levels of indoor pollutants, according to new research at the University of Georgia. Researchers showed that certain species can effectively ...



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