Atomic picture of dengue replication could transform antiviral approaches
A detailed atomic exploration into how the dengue virus replicates its genome could catalyze the development of high-precision targeted antiviral therapeutics.
A detailed atomic exploration into how the dengue virus replicates its genome could catalyze the development of high-precision targeted antiviral therapeutics.
Cell & Microbiology
Oct 31, 2023
0
1
When a human consumes a pharmaceutical drug, enzymes in the liver break down the substance into metabolites that are water soluble, so the body can more easily excrete them. In some cases, the resulting metabolites may have ...
Biochemistry
Jul 13, 2023
0
9
In the medicine market, most newly introduced drugs and drug candidates show poor water solubility, which prevents their absorption in the body. This, in turn, limits their therapeutic efficiency. Solubilizing agents such ...
Biochemistry
May 15, 2023
0
48
A new publication in the May issue of Nature Aging by researchers from Integrated Biosciences, a biotechnology company combining synthetic biology and machine learning to target aging, demonstrates the power of artificial ...
Biotechnology
May 8, 2023
0
6800
A research team co-led by chemists from City University of Hong Kong (CityU) recently discovered novel, highly effective anticancer agents with tridimensional structures, which have high anticancer activity, low toxicity ...
Biochemistry
Apr 6, 2023
0
18
A team of chemists at MIT has found that using peptides instead of DNA fragments to tag small molecules can speed up the drug discovery process. Their research is published in the journal Science.
Developing life-saving medicines can take billions of dollars and decades of time, but University of Central Florida researchers are aiming to speed up this process with a new artificial intelligence-based drug screening ...
Biotechnology
Sep 22, 2022
0
7
A new paper on cybervetting says that organizations need to develop and implement clearly defined rules regarding how they use online information about job candidates. Failing to better regulate their use of cybervetting ...
Social Sciences
Sep 13, 2022
0
17
Scientists at EPFL have found a way to synthesize large numbers of macrocyclic compounds, which are needed for developing drugs against difficult disease targets.
Biochemistry
Jul 12, 2022
0
28
Modern drug discovery is an expensive and complicated process. Hundreds of scientists and at least a decade are often required to produce a single medicine. One of the most critical steps in this process is the first one—identifying ...
Biochemistry
Apr 21, 2022
0
10