Inspired by what human liver enzymes can do, Scripps Research chemists have developed a new set of copper-catalyzed organic synthesis reactions for building and modifying pharmaceuticals and other molecules. The new reactions ...
Analytical Chemistry
14 hours ago
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17
The beginning of life on Earth and its evolution over billions of years continue to intrigue researchers worldwide. The central dogma or the directional flow of genetic information from a deoxyribose nucleic acid (DNA) template ...
Molecular & Computational biology
Apr 18, 2024
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110
A recent UCLA study demonstrates a new process for screening T cells, part of the body's natural defenses, for characteristics vital to the success of cell-based treatments. The method filters T cells based on the receptor ...
Bio & Medicine
Apr 15, 2024
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46
Researchers have discovered ways to convert inhibitor-style targeted cancer drugs into small molecules known as degraders, which help destroy cancer-promoting proteins in cells.
Biochemistry
Apr 11, 2024
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34
A recent breakthrough sheds light on how the malaria parasite, Plasmodium falciparum, invades human red blood cells. The study, led by the Swiss Tropical and Public Health Institute (Swiss TPH) and Griffith University's Institute ...
Cell & Microbiology
Apr 3, 2024
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0
For the first time, scientists from the University of Cologne (UoC) have developed artificial nucleotides, the building blocks of DNA, with several additional properties in the laboratory, which could be used as artificial ...
Biotechnology
Mar 8, 2024
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89
Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infections—and, alas, extraordinarily difficult to target with drugs.
Biochemistry
Mar 7, 2024
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31
Vanderbilt scientist Houra Merrikh led a team of researchers who discovered the first anti-evolution chemical compound that prevents drug resistance development in bacteria. The compound is also a drug development platform ...
Biochemistry
Feb 29, 2024
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15
An online platform powered by deep learning can predict the makeup of new psychoactive substances to help law enforcement in the fight against dangerous drugs.
Analytical Chemistry
Feb 29, 2024
2
13
A research team from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences / IOCB Prague has developed a novel computational method that can accurately describe how proteins interact with molecules ...
Analytical Chemistry
Feb 20, 2024
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