Towards synthesis of phenanthridine-based pharmaceutical compounds

Phenanthridines are heterocyclic compounds consisting of two six-membered benzene rings fused to a six-membered ring containing nitrogen. They are found in many naturally occurring organic compounds known for their anticancer ...

Light and nickel found to simplify cross-coupling reactions

Cross-coupling reactions—chemical transformations in which two fragments are joined together—are a valuable tool in the synthesis of organic molecules. Applications range from drug development and synthesis of naturally ...

Study examines how DNA damage is repaired by antioxidant enzymes

A typical human cell is metabolically active, roaring with chemical reactions that convert nutrients into energy and useful products that sustain life. These reactions also create reactive oxygen species, dangerous by-products ...

Using AI to create better, more potent medicines

While it can take years for the pharmaceutical industry to create medicines capable of treating or curing human disease, a new study suggests that using generative artificial intelligence could vastly accelerate the drug-development ...

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