Vanderbilt scientist Houra Merrikh led a team of researchers who discovered the first anti-evolution chemical compound that prevents drug resistance development in bacteria. The compound is also a drug development platform ...
Biochemistry
Feb 29, 2024
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15
November 24 marked 164 years since the publication of Charles Darwin's revolutionary "On the Origin of Species," one of the most influential scientific books ever written. In acknowledgement, 24 November is known as "Evolution ...
Evolution
Nov 27, 2023
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0
The drugs used to treat and prevent malaria in Mozambique are still effective, according to a genomic analysis of drug resistance markers in P. falciparum, carried out by the Barcelona Institute for Global Health (ISGlobal) ...
Cell & Microbiology
Jun 21, 2023
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28
How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene. Now, thanks to a combination of field and lab studies, an international research team has shown a second ...
Cell & Microbiology
May 11, 2023
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59
When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic ...
Cell & Microbiology
May 9, 2022
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16
Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial infection that has become resistant to most of the antibiotics used to treat regular staph infections. Duke University computer scientist Bruce Donald and ...
Molecular & Computational biology
Feb 17, 2022
1
208
Scientists have developed a mathematical model that predicts how the number and effects of bacterial mutations leading to drug resistance will influence the success of antibiotic treatments.
Molecular & Computational biology
May 18, 2021
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9
Bacteria can still develop antibiotic resistance even in the face of challenging genetic tradeoffs, or compromises, associated with varying antibiotic concentrations, says a new study published today in eLife.
Cell & Microbiology
May 19, 2020
0
3
To counter drug resistance, scientists engineer new drugs to "fit" new mutations and thus kill the cancer cell or pathogen. Now, an NIBIB-funded team of Penn State engineers has a new approach for predicting which mutation ...
Cell & Microbiology
May 13, 2020
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19
Whether it is a drug-resistant strain of bacteria, or cancer cells that no longer react to the drugs intended to kill them, diverse mutations make cells resistant to chemicals, and "second generation" approaches are needed. ...
Biotechnology
Mar 24, 2020
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