News tagged with drug target
Mirror images united: Simultaneous binding of both enantiomers of a drug to an enzyme
Oct 29, 2009 |
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(PhysOrg.com) -- In the binding pockets of enzymes their natural binding partners fit exactly. The principle by which many pharmacological agents work also relies on the fact that these substances fit exactly into the pockets ...
Mutated FGFR4 protein helps a childhood cancer spread
Oct 05, 2009 |
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Rhabdomyosarcoma (RMS) is a childhood cancer thought to originate from skeletal muscle. In patients whose disease has spread (metastasized) from the initial tumor site the chance of long-term survival is poor. Hopes for a ...
Yeast unravels effects of chemotherapy drugs
Sep 09, 2009 |
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Until now, the mode of action of nitrogen-containing bisphosphonate (N-BP) cancer drugs, used to relieve bone pain and to prevent skeletal complications in bone metastasis, has been almost entirely unknown. Researchers writing ...
Research points to new target for stopping colon cancer
Aug 17, 2009 |
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New research led by scientists at the University of North Carolina at Chapel Hill School of Medicine have found a drug target that suggests a potent way to kill colon cancers that resist current drugs aimed at blocking a ...
Novel genetic finding offers new avenue for future Crohn's disease treatment
Jul 09, 2009 |
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Researchers from Case Western Reserve University School of Medicine identified a novel link between ITCH, a gene known to regulate inflammation in the body and NOD2, a gene which causes the majority of genetic Crohn's Disease ...
Possible drug target found for one of the most aggressive breast cancers
Jul 08, 2009 |
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Van Andel Research Institute (VARI) investigators have identified a gene that could be an important therapeutic target in the treatment of the most aggressive forms of breast cancer. Currently, patients with these cancers ...
New findings reveal how influenza virus hijacks human cells
Biology /
Feb 04, 2009 |
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Influenza is and remains a disease to reckon with. Seasonal epidemics around the world kill several hundred thousand people every year. In the light of looming pandemics if bird flu strains develop the ability ...
Researchers identify potential new drug target for chronic leukemia
Nov 24, 2008 |
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Researchers at the University of California, San Diego (UCSD) and the Moores UCSD Cancer Center have discovered what could be a novel drug target for an often difficult-to-treat form of leukemia. The investigators have identified ...
Discovery offers new understanding of diabetes drug target
Biology /
Sep 26, 2008 |
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Scientists at the University of Leicester have published findings about a new advance in the study of major diabetes drug target.
