News tagged with egfr
Which is promising as therapeutic targets in patients with biliary tract cancer? EGFR or HER2?
Oct 16, 2009 |
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A research team from Germany analyzed the pathogenetic role and potential clinical usefulness of the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2) in patients with advanced ...
Vandetanib shows clinical benefit when combined with docetaxel for lung cancer
Jun 01, 2009 |
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When combined with standard chemotherapy, an international Phase III trial has shown that the oral targeted therapy vandetanib improves progression-free survival for patients with advanced non-small cell lung cancer, according ...
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EGFR protects cancer cells from starvation via a kinase-independent mechanism
May 05, 2008 |
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Scientists have uncovered a previously unrealized mechanism by which the epidermal growth factor receptor (EGFR), a tyrosine kinase, promotes survival of cancer cells through a kinase-independent mechanism. The research, ...
Protein inhibits cancer cell growth
Dec 21, 2009 |
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(PhysOrg.com) -- Researchers at the University of Toronto and Goethe University in Germany have discovered a protein that can inhibit the growth of cancer cells, providing crucial clues for the future development of new drugs ...
Larger labs report kidney function routinely
Oct 14, 2008 |
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Labs that conduct the highest number of routine blood tests are more likely than others to report estimated glomerular filtration rate (eGFR), an important measure of kidney function that can identify early kidney disease, ...
Molecule plays early role in nonsmoking lung cancer
Jul 27, 2009 |
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The cause of lung cancer in never-smokers is poorly understood, but a study led by investigators at the Ohio State University Comprehensive Cancer Center and at the National Cancer Institute has identified a molecule believed ...
Knockdown of E2F1 reduces invasive potential of melanoma cells
Dec 23, 2009 |
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Inhibition of transcription factor E2F1 reduced epidermal growth factor receptor (EGFR) expression and reduced the invasive potential but not proliferation of metastatic melanoma cells, according to a brief communication ...
Targeting brain cancer cell metabolism may provide new treatment
Dec 15, 2009 |
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Inhibiting fatty acid synthesis in brain cancer cells may offer a new option to treat about 50 percent of deadly glioblastomas that are driven by amplified signaling of the epidermal growth factor receptor (EGFR), according ...
How can we know early who will benefit from tumor target therapy?
Nov 21, 2007 |
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The precise tailoring of tumor target treatment for patients with cancer is an unmet challenge. The goal is to only administer treatments that have a high probability of being effective. Modern cancer care is critically dependent ...
African American lung cancer patients may have different response to new cancer-fighting drugs
Oct 07, 2009 |
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Clinical research out of University Hospitals Case Medical Center has found that African Americans with a common form of lung cancer have a lower frequency of drug-sensitizing genetic mutations, which may impact response ...
Gefitinib improves survival compared with standard chemotherapy in lung cancer patients with genetic mutation
Dec 20, 2009 |
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Patients with the most common form of lung cancer (non-small-cell lung cancer) who have mutations in the epidermal growth factor receptor (EGFR) gene have significantly improved progression-free survival if they are treated ...
Fruit fly protein acts as decoy to capture tumor growth factors
May 28, 2008 |
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Researchers at the University of Pennsylvania School of Medicine have shown how Argos, a fruit fly protein, acts as a 'decoy' receptor, binding growth factors that promote the progression of cancer. Knowing ...
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