Attaching chains of the small molecule ADP-ribose to proteins is important for a cell's survival and the repair of DNA damage, making this process a promising target for the development of new cancer drugs. Researchers have ...
Cell & Microbiology
Mar 12, 2013
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Rapidly dividing cancer cells are skilled at patching up damage that would stop normal cells in their tracks, including wear and tear of telomeres, the protective caps at the end of each chromosome.
Cell & Microbiology
Mar 21, 2012
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Human pluripotent stem cells, which can develop into any cell type in the body, rely heavily on glycolysis, or sugar fermentation, to drive their metabolic activities.
Cell & Microbiology
Nov 15, 2011
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(PhysOrg.com) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI) are the first to establish a direct link between a conserved stem cell factor and the cell cycle regulation in adult stem cells. ...
Cell & Microbiology
Sep 2, 2011
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A basic requirement for growth and life of a multicellular organism is the ability of its cells to divide. A protein complex, the so-called centrosome, plays a major role during cell division. Scientists at the Max Planck ...
Biotechnology
Sep 6, 2010
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(PhysOrg.com) -- A protein complex, which is an important link in a cellular transport chain, also initiates the assembly of the next link in the chain. This newly-won insight will now allow a better understanding of a transport ...
Cell & Microbiology
May 25, 2010
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A viral infection is like an uninvited, tenacious houseguest in the cell, using a range of tricks to prevent its eviction. Researchers at the Salk Institute for Biological Studies have identified one of the key proteins allowing ...
Cell & Microbiology
Jan 21, 2010
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Scientists at the University of Bonn, Germany, have discovered a previously unknown fruit fly gene that controls the metabolism of fat. Larvae in which this gene is defective lose their entire fat reserves. Therefore the ...
Biotechnology
Nov 2, 2009
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(PhysOrg.com) -- Research at the University of Cincinnati has led to the first published structure of myostatin, a protein that regulates muscle growth in animals, offering hope for major advances in the fight against muscle-wasting ...
Cell & Microbiology
Jul 30, 2009
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Inflammation, the body's earliest response to damage or infection, can aid the healing process and trigger an immune response against invading pathogens. But inflammation gone awry can also undermine health, as in diseases ...
Cell & Microbiology
Mar 11, 2009
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