Team uncovers the underlying mechanisms of 3-D tissue formation

If you want to build an organ for transplant, you need to think in 3-D. Using stem cells, scientists are now able to grow parts of organs in the lab, but that is a far cry from constructing a fully-formed, functioning, three-dimensional ...

A first look at the earliest decisions that shape a human embryo

The factors that shape the destiny of a cell, like that of a fully formed person, remain something of a mystery. Why, for example, does one stem cell in a human embryo become a neuron rather than a muscle cell? And why does ...

Measuring the hardness of living tissues without damage

When a fertilized egg is developing into a fetus, cell populations forming tissues are in a fluid state, and thus, the tissue can be easily deformed. Cells also generate mechanical forces during development that contribute ...

Tissue mechanics essential for cell movement

Cells that form facial features need surrounding embryonic tissues to stiffen so they can move and develop, according to new UCL-led research.

Understanding the language of cellular communication

A team of Caltech scientists has uncovered a molecular code that cells use to communicate with each other. This "language" is thought to be common to many types of cellular communication and has implications for designing ...

Friction shapes zebrafish embryos

A simple ball of cells is the starting point for humans—and zebrafish. At the end of embryonic development, however, a fish and a human look very different. The biochemical signals at play have been studied extensively. ...

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