Enzyme

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Enzymes are biomolecules that catalyze (i.e., increase the rates of) chemical reactions. Nearly all known enzymes are proteins. However, certain RNA molecules can be effective biocatalysts too. These RNA molecules have come to be known as ribozymes. In enzymatic reactions, the molecules at the beginning of the process are called substrates, and the enzyme converts them into different molecules, called the products. Almost all processes in a biological cell need enzymes to occur at significant rates. Since enzymes are selective for their substrates and speed up only a few reactions from among many possibilities, the set of enzymes made in a cell determines which metabolic pathways occur in that cell.

Like all catalysts, enzymes work by lowering the activation energy (Ea or ΔG‡) for a reaction, thus dramatically increasing the rate of the reaction. Most enzyme reaction rates are millions of times faster than those of comparable un-catalyzed reactions. As with all catalysts, enzymes are not consumed by the reactions they catalyze, nor do they alter the equilibrium of these reactions. However, enzymes do differ from most other catalysts by being much more specific. Enzymes are known to catalyze about 4,000 biochemical reactions. A few RNA molecules called ribozymes catalyze reactions, with an important example being some parts of the ribosome. Synthetic molecules called artificial enzymes also display enzyme-like catalysis.

Enzyme activity can be affected by other molecules. Inhibitors are molecules that decrease enzyme activity; activators are molecules that increase activity. Many drugs and poisons are enzyme inhibitors. Activity is also affected by temperature, chemical environment (e.g., pH), and the concentration of substrate. Some enzymes are used commercially, for example, in the synthesis of antibiotics. In addition, some household products use enzymes to speed up biochemical reactions (e.g., enzymes in biological washing powders break down protein or fat stains on clothes; enzymes in meat tenderizers break down proteins, making the meat easier to chew).

For more information about Enzyme, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.


News tagged with enzyme

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The hidden lives of proteins

The hidden lives of proteins

Chemistry / Biochemistry

created 16 hours ago | popularity 5 / 5 (2) | comments 0

An important Brandeis study appearing in the December 3 issue of Nature raises the curtain on the hidden lives of proteins at the atomic level. The study reports that for the first time, researchers used x ...


Scientists show how ubiquitin chains are added to cell-cycle proteins

Scientists show how ubiquitin chains are added to cell-cycle proteins

Biology / Cell & Microbiology

created 18 hours ago | popularity 4.7 / 5 (3) | comments 0

Researchers from the California Institute of Technology (Caltech) have been able to view in detail, and for the first time, the previously mysterious process by which long chains of a protein called ubiquitin ...


Kangaroos may hold skin cancer cure: study

Medicine & Health / Cancer

created Nov 30, 2009 | popularity not rated yet | comments 0

Kangaroos may provide the key to a potential treatment to prevent skin cancer, Australian scientists said Monday.


Long-term physical activity has an anti-aging effect at the cellular level

Medicine & Health / Health

created Nov 30, 2009 | popularity 4.5 / 5 (2) | comments 0

Intensive exercise prevented shortening of telomeres, a protective effect against aging of the cardiovascular system, according to research reported in Circulation: Journal of the American Heart Association.


An end to sleep problems? Researchers discover enzyme behind effects of sleep deprivation

Medicine & Health / Research

created Nov 26, 2009 | popularity 4 / 5 (1) | comments 0

There is hope for those who miss one night too many or whose children keep them up at night. The unwelcome effects of a bad night's sleep - forgetfulness, impaired mental performance - can be dealt with by reducing the concentration ...