News tagged with epidermal growth factor receptor
Early-stage, HER2-positive breast cancer patients at increased risk of recurrence
Nov 02, 2009 |
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Early-stage breast cancer patients with HER2 positive tumors one centimeter or smaller are at significant risk of recurrence of their disease, compared to those with early-stage disease who do not express the aggressive protein, ...
Which is promising as therapeutic targets in patients with biliary tract cancer? EGFR or HER2?
Oct 16, 2009 |
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A research team from Germany analyzed the pathogenetic role and potential clinical usefulness of the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2) in patients with advanced ...
Study finds that lung cancer patients respond to erlotinib following cetuximab therapy
Aug 02, 2009 |
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Non-small cell lung cancer patients who have progressed on a cetuximab-containing regimen may respond to erlotinib, Fox Chase Cancer Center researchers reported today at the annual meeting of the International Association ...
African-American women with advanced breast cancer often forego vital treatment
May 22, 2009 |
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A new study finds that nearly one in four African American women with late stage breast cancer refused chemotherapy and radiation therapy, potentially life saving therapies. Published in the July 1, 2009 issue of Cancer, a peer ...
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Newly discovered epidermal growth factor receptor active in human pancreatic cancers
Apr 19, 2009 |
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Finally some promising news about pancreatic cancer, one of the most fatal cancers, due to the difficulties of early detection and the lack of effective therapies: Johns Hopkins University pathologist Akhilesh Pandey has ...
Fruit fly protein acts as decoy to capture tumor growth factors
May 28, 2008 |
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Researchers at the University of Pennsylvania School of Medicine have shown how Argos, a fruit fly protein, acts as a 'decoy' receptor, binding growth factors that promote the progression of cancer. Knowing ...
Research points to new target for stopping colon cancer
Aug 17, 2009 |
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New research led by scientists at the University of North Carolina at Chapel Hill School of Medicine have found a drug target that suggests a potent way to kill colon cancers that resist current drugs aimed at blocking a ...
High throughput microscopy quantifies regulation of estrogen receptor
May 28, 2008 |
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High throughput microscopy that uses robots and special microscopes and techniques to generate thousands of images of a cell in a short time enabled researchers at Baylor College of Medicine in Houston to describe how the ...
Blood clotting protein may inhibit spinal cord regeneration
Jul 03, 2007 |
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Fibrinogen, a blood-clotting protein found in circulating blood, has been found to inhibit the growth of central nervous system neuronal cells, a process that is necessary for the regeneration of the spinal ...
Newly appreciated membrane estrogen receptor important therapeutic target for breast cancer
Jul 01, 2009 |
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New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer. The study is published in ...
New treatment combination proves safe for head and neck cancer patients
May 31, 2009 |
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Patients undergoing treatment for advanced head and neck cancers may respond well to the addition of gefinitib to chemotherapy, according to a study sponsored by the Eastern Cooperative Oncology Group and chaired by Ethan ...
A new take on growth factor signaling in tamoxifen resistance
Jun 24, 2009 |
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Differences in growth factor (GF) signaling may cause the poor prognosis in some breast cancer cases. A new study, published in the open access journal BMC Medical Genomics, suggests that some estrogen receptor-positive breast ...
Growth factor receptor affects prostate cancer progression
Dec 10, 2007 |
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Breeding mice with a gene for a cellular receptor that can be turned on and off-at will-not only enabled researchers at Baylor College of Medicine in Houston to show how prostate cancer progresses, but also provides a model ...
Vandetanib shows clinical benefit when combined with docetaxel for lung cancer
Jun 01, 2009 |
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When combined with standard chemotherapy, an international Phase III trial has shown that the oral targeted therapy vandetanib improves progression-free survival for patients with advanced non-small cell lung cancer, according ...
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