Epidermal growth factor
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Epidermal growth factor or EGF is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR. Human EGF is a 6045-Da protein with 53 amino acid residues and three intramolecular disulfide bonds.
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News tagged with epidermal growth factor
Early-stage, HER2-positive breast cancer patients at increased risk of recurrence
Nov 02, 2009 |
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Early-stage breast cancer patients with HER2 positive tumors one centimeter or smaller are at significant risk of recurrence of their disease, compared to those with early-stage disease who do not express the aggressive protein, ...
Which is promising as therapeutic targets in patients with biliary tract cancer? EGFR or HER2?
Oct 16, 2009 |
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A research team from Germany analyzed the pathogenetic role and potential clinical usefulness of the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2) in patients with advanced ...
Prodrug could help curb skin toxicity related to EGFR-inhibiting cancer drugs
Sep 01, 2009 |
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There may be a way around the harsh skin toxicity associated with a widely used cancer drug, according to a study published online this week in Cancer Biology and Therapy by researchers from City of Hope and the Kimmel Cancer ...
Research points to new target for stopping colon cancer
Aug 17, 2009 |
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New research led by scientists at the University of North Carolina at Chapel Hill School of Medicine have found a drug target that suggests a potent way to kill colon cancers that resist current drugs aimed at blocking a ...
Study finds that lung cancer patients respond to erlotinib following cetuximab therapy
Aug 02, 2009 |
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Non-small cell lung cancer patients who have progressed on a cetuximab-containing regimen may respond to erlotinib, Fox Chase Cancer Center researchers reported today at the annual meeting of the International Association ...
Vandetanib shows clinical benefit when combined with docetaxel for lung cancer
Jun 01, 2009 |
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When combined with standard chemotherapy, an international Phase III trial has shown that the oral targeted therapy vandetanib improves progression-free survival for patients with advanced non-small cell lung cancer, according ...
New treatment combination proves safe for head and neck cancer patients
May 31, 2009 |
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Patients undergoing treatment for advanced head and neck cancers may respond well to the addition of gefinitib to chemotherapy, according to a study sponsored by the Eastern Cooperative Oncology Group and chaired by Ethan ...
African-American women with advanced breast cancer often forego vital treatment
May 22, 2009 |
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A new study finds that nearly one in four African American women with late stage breast cancer refused chemotherapy and radiation therapy, potentially life saving therapies. Published in the July 1, 2009 issue of Cancer, a peer ...
First noninvasive technique to accurately predict mutations in human brain tumors
Apr 20, 2009 |
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Donald O'Rourke, MD, Associate Professor of Neurosurgery at the University of Pennsylvania School of Medicine and colleagues, were able to accurately predict the specific genetic mutation that caused brain cancer in a group ...
Newly discovered epidermal growth factor receptor active in human pancreatic cancers
Apr 19, 2009 |
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Finally some promising news about pancreatic cancer, one of the most fatal cancers, due to the difficulties of early detection and the lack of effective therapies: Johns Hopkins University pathologist Akhilesh Pandey has ...
