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News tagged with er stress

Unexpected signaling role for foul-smelling hydrogen sulfide in cell response to protein misfolding

Something rotten never smelled so sweet. This is what members of a team of scientists at Cold Spring Harbor Laboratory (CSHL) are telling one another as they discuss a new finding they did not expect to make. They have discovered ...

Medicine & Health / Research

created Dec 13, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New tactic for controlling blood sugar in diabetes contradicts current view of the disease

Increased low-grade inflammation in the body resulting from obesity is widely viewed as contributing to type 2 diabetes. Going against this long-held belief, researchers from Children's Hospital Boston report that two proteins ...

Medicine & Health / Research

created Sep 04, 2011 | popularity 4.8 / 5 (9) | comments 1 | with audio podcast

Unearthing a pathway to brain damage

Neuroscientists have long suspected that abnormal calcium signaling and accumulation of misfolded proteins cause an intracellular membrane-bound organelle called the endoplasmic reticulum (ER) to trigger the ...

Medicine & Health / Neuroscience

created Feb 25, 2011 | popularity not rated yet | comments 0

New mechanism links cellular stress and brain damage

A new study uncovers a mechanism linking a specific type of cellular stress with brain damage similar to that associated with neurodegenerative disease. The research, published by Cell Press in the December 9 issue of the ...

Medicine & Health / Neuroscience

created Dec 08, 2010 | popularity 5 / 5 (2) | comments 0

Level of cellular stress determines longevity of retinal cells

(PhysOrg.com) -- Stress can be adaptive. It can make you sharper, help you focus and it can even improve your performance. But too much of it can tax cells to the point where they can no longer cope and slowly ...

Medicine & Health / Research

created Apr 28, 2009 | popularity 5 / 5 (1) | comments 0

Obesity: Reviving the promise of leptin

(PhysOrg.com) -- The discovery more than a decade ago of leptin, an appetite-suppressing hormone secreted by fat tissue, generated headlines and great hopes for an effective treatment for obesity. But hopes ...

Biology /

created Jan 06, 2009 | popularity 4 / 5 (1) | comments 0