Estrogen receptor
hideEstrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. This article refers to the nuclear hormone receptor ER.
The main function of the estrogen receptor is as a DNA binding transcription factor that regulates gene expression. However, the estrogen receptor has additional functions independent of DNA binding.
For more information about Estrogen receptor, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
News tagged with estrogen receptor
FDA-approved drugs eliminate, prevent cervical cancer in mice
Nov 09, 2009 |
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Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have eliminated cervical cancer in mice with two FDA-approved drugs currently used to treat breast cancer and osteoporosis.
Cancer predisposition from genetic variation shows strong gender bias
Sep 21, 2009 |
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(PhysOrg.com) -- Cancer predisposition resulting from the presence of a specific gene variant shows a strong gender bias, researchers at the University of Cincinnati (UC) have demonstrated.
Low-dose estrogen shown safe and effective for metastatic breast cancer
Aug 18, 2009 |
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When estrogen-lowering drugs no longer control metastatic breast cancer, the opposite strategy might work. Raising estrogen levels benefited 30 percent of women whose metastatic breast cancer no longer responded to standard ...
DACH1 a key protein for tumor suppression in ER+ breast cancer
Jul 15, 2009 |
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Researchers from the Kimmel Cancer Center at Jefferson have identified a protein relationship that may be an ideal treatment target for ER+ breast cancer. The study was reported in the July 15 issue of Cancer Research.
Study identifies how tamoxifen stimulates uterine cell growth and cancer
Jul 02, 2009 |
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UCSF researchers have identified a new "feed-forward" pathway linking estrogen receptors in the membrane of the uterus to a process that increases local estrogen levels and promotes cell growth.
Risk of breast cancer and a single-nucleotide polymorphism
Jul 02, 2009 |
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The single-nucleotide polymorphism (SNP) known as 2q35-rs13387042 is associated with increased risk of estrogen receptor (ER) -positive and -negative breast cancer, according to a study published online July 1 in the Journal of ...
Newly appreciated membrane estrogen receptor important therapeutic target for breast cancer
Jul 01, 2009 |
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New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer. The study is published in ...
Evolution of a contraceptive for sea lamprey
Jun 25, 2009 |
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(PhysOrg.com) -- In addition to providing fundamental insights into the early evolution of the estrogen receptor, research by a team at the University of California, San Diego School of Medicine may lead to ...
PET scan can non invasively measure early assessment of treatment for common type of breast cancer
May 26, 2009 |
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Non-invasive imaging can measure how well patients with the most common form of breast cancer - estrogen receptor positive type - respond to standard aromatase inhibitor therapy after only two weeks and shows similar findings ...
Researchers: tamoxifen's power comes from endoxifen
Dec 11, 2008 |
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Mayo Clinic researchers have discovered that a chemical known as endoxifen appears to be the primary metabolite responsible for the effectiveness of tamoxifen in treating breast cancer, and that it works against cancer in ...
Improved estrogen reception may sharpen fuzzy memory
Jul 29, 2008 |
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Estrogen treatments may sharpen mental performance in women with certain medical conditions, but University of Florida researchers suggest that recharging a naturally occurring estrogen receptor in the brain may also clear ...
