A novel biosensor to detect DNA damage in real time

Double-strand breaks (DSBs) are a type of DNA damage where both strands of DNA break at the same location. They can adversely affect cell growth and functioning. Currently, DSBs are detected by immunostaining techniques, ...

FRET-based biosensor visualizes execution of necroptosis in vivo

Necroptosis is a form of regulated cell death (RCD) similar to apoptosis, the most commonly studied type of RCD. In contrast to apoptosis, plasma membrane rupture in necroptotic cells occurs at early time points. For this ...

Scientists reveal how detergents actually work

Scientists have discovered the precise way detergents break biological membranes, which could increase our understanding of how soaps work to kill viruses like COVID-19.

How a shape-shifting receptor influences cell growth

Receptors found on cell surfaces bind to hormones, proteins, and other molecules, helping cells respond to their environment. MIT chemists have now discovered how one of these receptors changes its shape when it binds to ...

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