Antidepressants polluting the water can change fish behavior

The Monash scientists who found that pharmaceutical pollutants in waterways altered reproductive behavior, anxiety levels, activity and antipredator responses of fish have now discovered for the first time that such toxicity ...

Study eyes fluoxetine in recreational waters

Mercyhurst College's research of contaminants in the recreational waters at Presque Isle State Park got a $250,000 boost from the U.S. Environmental Protection Agency, it was announced today.

Antidepressants make shrimps see the light

(PhysOrg.com) -- Rising levels of antidepressants in coastal waters could change sea-life behaviour and potentially damage the food-chain, according to a new study.

Fluoxetine

Fluoxetine (also known by the tradenames Prozac, Sarafem, Fontex) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is manufactured and marketed by Eli Lilly and Company. In combination with olanzapine it is known as Symbyax.

Fluoxetine is approved for the treatment of major depression (including pediatric depression), obsessive-compulsive disorder (in both adult and pediatric populations), bulimia nervosa, panic disorder and premenstrual dysphoric disorder.

Despite the availability of newer agents, fluoxetine remains extremely popular. In 2010, over 24.4 million prescriptions for generic formulations of fluoxetine were filled in the United States alone, making it the third most prescribed antidepressant after sertraline (SSRI; became generic in 2006) and citalopram (SSRI; became generic in 2003) in that country.

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