News tagged with gamma secretase
Noncoding RNA may promote Alzheimer's disease
Researchers pinpoint a small RNA that spurs cells to manufacture a particular splice variant of a key neuronal protein, potentially promoting Alzheimer's disease (AD) or other types of neurodegeneration. The ...
May 30, 2011 |
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Alzheimer's disease drug treats traumatic brain injury
The destructive cellular pathways activated in Alzheimer's disease are also triggered following traumatic brain injury, say researchers from Georgetown University Medical Center (GUMC). They say this finding suggests that ...
Jul 12, 2009 |
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New insight into Alzheimer's disease pathology
An Alzheimer's-related protein helps form and maintain nerve cell connections, according to a study published in the May 4 print issue of the Journal of Cell Biology.
May 04, 2009 |
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Search results for gamma secretase
Asthma drug could help control or treat Alzheimer's disease
A drug used to treat asthma has been shown to help reduce the formation of amyloid beta, a peptide in the brain that is implicated in the development of Alzheimer's disease, according to researchers at Temple University's ...
Mar 25, 2011 |
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Scientists discover mechanism involved in breast cancer's spread to bone
In a discovery that may lead to a new treatment for breast cancer that has spread to the bone, a Princeton University research team has unraveled a mystery about how these tumors take root.
Feb 03, 2011 |
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Study raises safety concerns about experimental cancer approach
A study by researchers at Washington University School of Medicine in St. Louis has raised safety concerns about an investigational approach to treating cancer.
Jan 25, 2011 |
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Unlocking the secret(ase) of building neural circuits
Mutant presenilin is infamous for its role in the most aggressive form of Alzheimer's disease -- early-onset familial Alzheimer's -- which can strike people as early as their 30s. In their latest study, researchers ...
Jan 18, 2011 |
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Treating deadly brain tumors by combining drugs
Lab studies show that combining drugs that target a variety of developmental cell signaling pathways may do a better job of killing deadly brain tumors than single drugs that target one pathway at a time, according to a new ...
Jan 12, 2011 |
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Modulating a protein in the brain could help control Alzheimer's disease
A protein known to exist in the brain for more than 30 years, called 5-lipoxygenase, has been found to play a regulatory role in the formation of the amyloid beta in the brain, the major component of plaques implicated in ...
Medicine & Health / Neuroscience
Nov 18, 2010 |
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Researchers build colony of colon cancer stem cells to test new approach to therapy
University of Pittsburgh researchers have devised a three-dimensional system in laboratory culture that mimics the growth patterns of colon cancer stem cells in patients. Their findings were presented at the American Association ...
Oct 28, 2010 |
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Researchers find pathway that drives spread of pediatric bone cancer in preclinical studies
Researchers have identified an important signaling pathway that, when blocked, significantly decreases the spread of pediatric bone cancer.
Oct 25, 2010 |
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Compounds fend off Alzheimer's disease amyloid pathology
A team of scientists, led by University of California, San Diego School of Medicine researchers, has synthesized hundreds of new compounds with the potential of reducing the production of the A-beta 42 peptide, a primary ...
Medicine & Health / Neuroscience
Sep 08, 2010 |
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Scientists identify protein that spurs formation of Alzheimer's plaques
In Alzheimer's disease, the problem is beta-amyloid, a protein that accumulates in the brain and causes nerve cells to weaken and die. Drugs designed to eliminate plaques made of beta-amyloid have a fatal problem: they need ...
Sep 01, 2010 |
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List of search results for gamma secretase
