News tagged with gene regulation

Drugs targeting chromosomal instability may fight a particular breast cancer subtype

Another layer in breast cancer genetics has been peeled back. A team of researchers at Jefferson's Kimmel Cancer Center (KCC) led by Richard G. Pestell, M.D., PhD., FACP, Director of the KCC and Chair of the Department of ...

Medicine & Health / Cancer

created Feb 06, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Mechanism sheds light on how the brain adapts to stress

Scientists now have a better understanding of the way that stress impacts the brain. New research, published by Cell Press in the January 26 issue of the journal Neuron, reveals pioneering evidence for a new mechanism of str ...

Medicine & Health / Neuroscience

created Jan 25, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study provides new insights into an ancient mechanism of mammalian evolution

A team of geneticists and computational biologists in the UK today reveal how an ancient mechanism is involved in gene control and continues to drive genome evolution. The new study is published in the journal ...

Biology / Biotechnology

created Jan 12, 2012 | popularity 4.6 / 5 (5) | comments 0 | with audio podcast

The machinery of chromatin regulation

Ten years after the human genome was first published, researchers have found new clues into the machinery that influences gene function. The team, led by Bradley Bernstein, an associate professor of pathology ...

Biology / Cell & Microbiology

created Dec 23, 2011 | popularity 5 / 5 (1) | comments 4

Transcriptional elongation control takes on new dimensions

Life is complicated enough, so you can forgive the pioneers of DNA biology for glossing over transcriptional elongation control by RNA polymerase II, the quick and seemingly bulletproof penultimate step in ...

Biology / Cell & Microbiology

created Dec 22, 2011 | popularity 5 / 5 (1) | comments 0

Gene found in humans, mice protects cornea transparency

A transparent cornea is essential for vision, which is why the eye has evolved to nourish the cornea without blood vessels. But for millions of people around the world, diseases of the eye or trauma spur the growth of blood ...

Medicine & Health / Genetics

created Dec 12, 2011 | popularity not rated yet | comments 0 | with audio podcast

Orphaned children exhibit genetic changes that require nurturing parents

Children who experience the stress of separation at birth from biological parents and are brought up in orphanages undergo biological consequences such as changes in their genome functioning, Yale School of ...

Medicine & Health / Psychology & Psychiatry

created Dec 05, 2011 | popularity 5 / 5 (2) | comments 0

New genetic region responsible for testicle development found

New research presented today at the European Society for Paediatric Endocrinology meeting has found a genetic region, which may control testicle development in the foetus.

Medicine & Health / Genetics

created Sep 26, 2011 | popularity not rated yet | comments 0

Dundee researchers make gene breakthrough

Researchers at the University of Dundee have made a significant breakthrough in understanding how human cells decode genes important for cell growth and multiplication.

Biology / Biotechnology

created Sep 16, 2011 | popularity 5 / 5 (2) | comments 0

'TF beacons' may light path to new cancer tests and drugs

Scientists are reporting development of a long-sought new way to detect the activity of proteins that bind to the DNA in genes, often controlling the activity of genes in ways that make cells do everything ...

Chemistry / Biochemistry

created Sep 07, 2011 | popularity 5 / 5 (2) | comments 0

Sequencing platform provides powerful tool for identifying subtle changes in gene expression

In a truly challenging task, the FANTOM5 Consortium, an international collaboration headed by scientists at the RIKEN Omics Science Center in Yokohama, Japan, is striving to profile the regulation of gene ...

Biology / Biotechnology

created Sep 02, 2011 | popularity 5 / 5 (1) | comments 0

Three periods of innovation in gene regulation occurred during the evolution of vertebrate animals: study

Over the past 530 million years, the vertebrate lineage branched out from a primitive jawless fish wriggling through Cambrian seas to encompass all the diverse forms of fish, birds, reptiles, amphibians, and mammals. Now ...

Biology / Biotechnology

created Aug 18, 2011 | popularity 4.8 / 5 (5) | comments 0 | with audio podcast

Regulating the formation of fear extinction memory

(Medical Xpress) -- Neuroscientists at UQ's Queensland Brain Institute have discovered a previously unrecognized layer of gene regulation associated with fear extinction.

Medicine & Health / Neuroscience

created Aug 15, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientist discovers genetic factor implicated in heartbeat defect

A scientist at the Gladstone Institutes has discovered how gene regulation can make hearts beat out of sync, offering new hope for the millions who suffer from a potentially fatal heart condition.

Medicine & Health / Research

created Aug 08, 2011 | popularity not rated yet | comments 0 | with audio podcast

Novel DNA sequencer for MDC's systems biology

The Berlin Institute for Medical Systems Biology (BIMSB) of the Max Delbrück Center for Molecular Medicine (MDC) in Berlin, Germany, will be the first academic research institution in Continental Europe to acquire a ...

Biology / Cell & Microbiology

created Jul 15, 2011 | popularity not rated yet | comments 0

Regulation of gene expression

Gene modulation redirects here. For information on therapeutic regulation of gene expression, see therapeutic gene modulation.

Regulation of gene expression (or gene regulation) includes the processes that cells and viruses use to turn the information in genes into gene products. Although a functional gene product may be an RNA or a protein, the majority of known mechanisms regulate protein coding genes. Any step of the gene's expression may be modulated, from DNA-RNA transcription to the post-translational modification of a protein.

Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed. The first discovered example of a gene regulation system was the lac operon, discovered by Jacques Monod, in which protein involved in lactose metabolism are expressed by E.coli only in the presence of lactose and absence of glucose.

Furthermore, gene regulation drives the processes of cellular differentiation and morphogenesis, leading to the creation of different cell types in multicellular organisms where the different types of cells may possess different gene expression profiles though they all possess the same genome sequence.

For more information about Regulation of gene expression, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.