Regulation of gene expression
hideGene modulation redirects here. For information on therapeutic regulation of gene expression, see therapeutic gene modulation.
Regulation of gene expression (or gene regulation) includes the processes that cells and viruses use to turn the information in genes into gene products. Although a functional gene product may be an RNA or a protein, the majority of known mechanisms regulate protein coding genes. Any step of the gene's expression may be modulated, from DNA-RNA transcription to the post-translational modification of a protein.
Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed. The first discovered example of a gene regulation system was the lac operon, discovered by Jacques Monod, in which protein involved in lactose metabolism are expressed by E.coli only in the presence of lactose and absence of glucose.
Furthermore, gene regulation drives the processes of cellular differentiation and morphogenesis, leading to the creation of different cell types in multicellular organisms where the different types of cells may possess different gene expression profiles though they all possess the same genome sequence.
For more information about Regulation of gene expression, read the full article at
Wikipedia.
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News tagged with gene regulation
Technique finds gene regulatory sites without knowledge of regulators
Nov 19, 2009 |
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A new statistical technique developed by researchers at the University of Illinois allows scientists to scan a genome for specific gene-regulatory regions without requiring prior knowledge of the relevant transcription factors. ...
New research into the mechanisms of gene regulation
Nov 19, 2009 |
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(PhysOrg.com) -- A team led by Penn State's Ross Hardison, T. Ming Chu Professor of Biochemistry and Molecular Biology, has taken a large step toward unraveling how regulatory proteins control the production ...
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Scientists find clue to mystery of biological clock
Medicine & Health / Neuroscience
Nov 30, 2009 |
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How does our biological system know that it is supposed to operate on a 24-hour cycle? Scientists at the Hebrew University of Jerusalem have discovered that a tiny molecule holds the clue to the mystery.
Can cleft palate be healed before birth?
Dec 01, 2009 |
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In a study newly published in the journal Development, investigators at the USC School of Dentistry describe how to non-surgically reverse the onset of cleft palate in fetal mice - potentially one step in the journey to a b ...
Heart failure linked to gene variant affecting vitamin D activation
Dec 01, 2009 |
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Previous studies have shown a link between low vitamin D status and heart disease. Now a new study shows that patients with high blood pressure who possess a gene variant that affects an enzyme critical to normal vitamin ...
Tiny RNA has big impact on lung cancer tumors
Dec 07, 2009 |
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Researchers from Yale University and Mirna Therapeutics, Inc., reversed the growth of lung tumors in mice using a naturally occurring tumor suppressor microRNA. The study reveals that a tiny bit of RNA may one day play a ...
Gene linked to a rare form of progressive hearing loss in males is identified
Dec 17, 2009 |
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A gene associated with a rare form of progressive deafness in males has been identified by an international team of researchers funded by the National Institute on Deafness and Other Communication Disorders. The gene, PRPS1, ...
Acute stress leaves epigenetic marks on the hippocampus
Medicine & Health / Psychology & Psychiatry
Nov 24, 2009 |
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(PhysOrg.com) -- Scientists are learning that the dynamic regulation of genes -- as much as the genes themselves -- shapes the fate of organisms. Now the discovery of a new epigenetic mechanism regulating genes in the brain ...
Why Some Monkeys Don't Get AIDS
Medicine & Health / HIV & AIDS
Dec 03, 2009 |
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(PhysOrg.com) -- Two studies published this month in the Journal of Clinical Investigation provide a significant advance in understanding how some species of monkeys such as sooty mangabeys and African green ...
Feeding the clock: Cycles of feeding and fasting drive circadian gene expression in the liver
Nov 25, 2009 |
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When you eat may be just as vital to your health as what you eat, found researchers at the Salk Institute for Biological Studies. Their experiments in mice revealed that the daily waxing and waning of thousands ...
Dessert on your mind? Your muscles may be getting the message
Dec 01, 2009 |
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Even the anticipation of sweets may cause our muscles to start taking up more blood sugar, say researchers reporting in the December issue of Cell Metabolism. That message is delivered via neurons in the brain's hypothalamus contai ...
Research project yields better understanding of the defective protein that causes cystic fibrosis
Dec 18, 2009 |
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A team of researchers studying the protein that, when defective or absent, causes cystic fibrosis (CF) has made an important discovery about how that protein is normally controlled and under what circumstances ...
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