Gene therapy
hideGene therapy is the insertion of genes into an individual's cells and tissues to treat a disease, such as a hereditary disease in which a deleterious mutant allele is replaced with a functional one. Although the technology is still in its infancy, it has been used with some success. Antisense therapy is not strictly a form of gene therapy, but is a genetically-mediated therapy and is often considered together with other methods.
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News tagged with gene therapy
Scientists measure energy released from a virus during infection
Feb 05, 2010 |
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Within a virus's tiny exterior is a store of energy waiting to be unleashed. When the virus encounters a host cell, this pent-up energy is released, propelling the viral DNA into the cell and turning it into a virus factory. ...
Researchers develop new tool for gene delivery
Jan 27, 2010 |
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Researchers at Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts have developed a new tool for gene therapy that significantly increases gene delivery to cells in the retina ...
Researchers continue 'extraordinary measures' to tackle Pompe disease
Jan 26, 2010 |
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As scientists work to find new treatments for Pompe disease -- the devastating genetic "villain" that drives the efforts of the main characters in the new film "Extraordinary Measures" -- University of Florida researchers ...
I-1c gene therapy: Not such a good idea in heart failure?
Jan 12, 2010 |
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Several lines of evidence, including the observation that the protein I-1 is downregulated in human failing hearts, have led to the suggestion that gene therapy to express a constitutively active form of the protein (I-1c) ...
Researchers discover molecular security system that protects cells from potentially harmful DNA
Jan 10, 2010 |
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Researchers at the University of Minnesota have discovered a molecular security system in human cells that deactivates and degrades foreign DNA. This discovery could open the door to major improvements in genetic engineering ...
Sleeping Beauty hooks up with herpes to fight brain disease
Jan 08, 2010 |
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Neuroscientists have forged an unlikely molecular union as part of their fight against diseases of the brain and nervous system.
Heavy metal paradox could point toward new therapy for Lou Gehrig's disease
Medicine & Health / Neuroscience
Nov 30, 2009 |
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New discoveries have been made about how an elevated level of lead, which is a neurotoxic heavy metal, can slow the progression of amyotrophic lateral sclerosis, or Lou Gehrig's disease - findings that could point the way ...
Gene increases effectiveness of drugs used to fight cancer and allows reduction in dosage
Nov 24, 2009 |
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Researchers at the University of Granada, Spain, have found a suicide gene, called 'gene E', which leads to the death of tumour cells derived from breast, lung and colon cancer, and prevents their growth. ...
Gene therapy improves vision
Nov 23, 2009 |
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German scientist Paul Ehrlich found what he coined the "magic bullet" in the early 20th century upon developing the world’s first effective treatment of syphilis.
Research reveals lipids' unexpected role in triggering death of brain cells
Nov 12, 2009 |
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The lipid that accumulates in brain cells of individuals with an inherited enzyme disorder also drives the cell death that is a hallmark of the disease, according to new research led by St. Jude Children's Research Hospital ...
No-entry zones for AIDS virus
Medicine & Health / HIV & AIDS
Nov 12, 2009 |
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The AIDS virus inserts its genetic material into the genome of the infected cell. Scientists of the German Cancer Research Center have now shown for the first time that the virus almost entirely spares particular ...
Treatment to improve degenerating muscle gains strength
Nov 11, 2009 |
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A study appearing in Science Translational Medicine puts scientists one step closer to clinical trials to test a gene delivery strategy to improve muscle mass and function in patients with certain degenerative muscle disord ...
Nanoparticles for gene therapy improve
Nanotechnology / Bio & Medicine
Nov 06, 2009 |
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(PhysOrg.com) -- About five years ago, Professor Janet Sawicki at the Lankenau Institute in Pennsylvania read an article about nanoparticles developed by MIT's Robert Langer for gene therapy, the insertion ...
Gene therapy technique slows ALD brain disease
Nov 05, 2009 |
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A strategy that combines gene therapy with blood stem cell therapy may be a useful tool for treating a fatal brain disease, French researchers have found. These findings appear in the 6 November 2009 issue ...
Researchers show efficacy of gene therapy in mouse models of Huntington's disease
Medicine & Health / Neuroscience
Oct 30, 2009 |
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Researchers at the California Institute of Technology (Caltech) have shown that a highly specific intrabody (an antibody fragment that works against a target inside a cell) is capable of stalling the development of Huntington's ...
