Related topics: proceedings of the national academy of sciences , cells , protein , gene expression , fruit flies
Gene
hideA gene is the basic unit of heredity in a living organism. All living things depend on genes. Genes hold the information to build and maintain their cells and pass genetic traits to offspring. A modern working definition of a gene is "a locatable region of genomic sequence, corresponding to a unit of inheritance, which is associated with regulatory regions, transcribed regions, and or other functional sequence regions " . In common usage, the term gene often refers to what is known more accurately as an allele.
The notion of a gene has evolved with the science of genetics, which began when Gregor Mendel noticed that biological variations are inherited from parent organisms as specific, discrete traits. The biological entity responsible for defining traits was termed a gene, but the biological basis for inheritance remained unknown until DNA was identified as the genetic material in the 1940s. All organisms have many genes corresponding to many different biological traits, some of which are immediately visible, such as eye color or number of limbs, and some of which are not, such as blood type or increased risk for specific diseases, or the thousands of basic biochemical processes that comprise life.
In cells, a gene is a portion of DNA that contains both "coding" sequences that determine what the gene does, and "non-coding" sequences that determine when the gene is active (expressed). When a gene is active, the coding and non-coding sequences are copied in a process called transcription, producing an RNA copy of the gene's information. This piece of RNA can then direct the synthesis of proteins via the genetic code. In other cases, the RNA is used directly, for example as part of the ribosome. The molecules resulting from gene expression, whether RNA or protein, are known as gene products, and are responsible for the development and functioning of all living things.
In more technical terms, a gene is a locatable region of genomic sequence, corresponding to a unit of inheritance, and is associated with regulatory regions, transcribed regions and/or other functional sequence regions. The physical development and phenotype of organisms can be thought of as a product of genes interacting with each other and with the environment. A concise definition of a gene, taking into account complex patterns of regulation and transcription, genic conservation and non-coding RNA genes, has been proposed by Gerstein et al.: "A gene is a union of genomic sequences encoding a coherent set of potentially overlapping functional products".
For more information about Gene, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
News tagged with genes
Male and female shopping strategies show evolution at work in the mall
Other Sciences / Social Sciences
Dec 02, 2009 |
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Male and female shopping styles are in our genes---and we can look to evolution for the reason. Daniel Kruger, research faculty at the University of Michigan School of Public Health, says it's perfectly natural that men often ...
Scientists discover gene module underlying atherosclerosis development
Dec 04, 2009 |
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By measuring the total gene activity in organs relevant for coronary artery disease (CAD), scientists at the Swedish medical university Karolinska Institutet have identified a module of genes that is important for the recruitment ...
Mice holding back muscular dystrophy research
Dec 04, 2009 |
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Humans and mice have previously unknown and potentially critical differences in one of the genes responsible for Duchenne muscular dystrophy (DMD). Researchers writing in the open access journal BMC Biology have found that t ...
Why we outlive our ape ancestors
Dec 02, 2009 |
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In spite of their genetic similarity to humans, chimpanzees and great apes have maximum lifespans that rarely exceed 50 years. The difference, explains USC Davis School of Gerontology Professor Caleb Finch, is that as humans ...
Scientists find clue to mystery of biological clock
Medicine & Health / Neuroscience
Nov 30, 2009 |
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How does our biological system know that it is supposed to operate on a 24-hour cycle? Scientists at the Hebrew University of Jerusalem have discovered that a tiny molecule holds the clue to the mystery.
Western diets turn on fat genes
Nov 30, 2009 |
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Those extra helpings of gravy and dessert at the holiday table are even less of a help to your waistline than previously thought. According to a new research report recently appearing online in The FASEB Journal, a diet t ...
Scientists get up close to bacteria's toxic pumps
Nov 30, 2009 |
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Scientists are building a clearer image of the machinery employed by bacteria to spread antibiotic resistance or cause diseases such as whooping cough, peptic stomach ulcers and legionnaires' disease.
Secondhand smoke exposure in childhood increases lung cancer risk later in life
Dec 03, 2009 |
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Children exposed to secondhand cigarette smoke have an increased risk of developing lung cancer in adulthood, even if they never smoked.
Knockouts in human cells point to pathogenic targets
Nov 26, 2009 |
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(PhysOrg.com) -- Whitehead researchers have developed a new approach for genetics in human cells and used this technique to identify specific genes and proteins required for pathogens.
Acute stress leaves epigenetic marks on the hippocampus
Medicine & Health / Psychology & Psychiatry
Nov 24, 2009 |
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(PhysOrg.com) -- Scientists are learning that the dynamic regulation of genes -- as much as the genes themselves -- shapes the fate of organisms. Now the discovery of a new epigenetic mechanism regulating genes in the brain ...
Opposites attract: Monkeys choose mating partners with different genes
Nov 24, 2009 |
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The world's largest species of monkey 'chooses' mates with genes that are different from their own to guarantee healthy and strong offspring, according to a new research study.
The deciding factor: Empathy distinguishes modern humans from their primate ancestors
Nov 30, 2009 |
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(PhysOrg.com) -- What, exactly, distinguishes humans from apes? It’s certainly more than just our genes, renowned anthropologist Sarah Blaffer Hrdy told a Harvard audience recently (Nov. 18).
Single gene may cause curly hair
Nov 10, 2009 |
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(PhysOrg.com) -- Scientists in Australia have identified a single gene that strongly influences whether you have curly or straight hair.
New tools for prediction of disease progression in acute childhood leukemia
Nov 27, 2009 |
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(PhysOrg.com) -- Researchers at Uppsala University and University Children’s Hospital in Uppsala have devised powerful new tools for typing cells from children with acute lymphatic leukemia and for prediction of how children ...
Scientists identify DNA that regulates antibody production
Nov 20, 2009 |
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(PhysOrg.com) -- When foreign invaders trip the immune system’s alarm, antibodies need to be specially sculpted to attack them head on. New research now shows that gene segments called enhancers control the reshuffling of ...
