Mutation
hideIn biology, mutations are changes to the nucleotide sequence of the genetic material of an organism. Mutations can be caused by copying errors in the genetic material during cell division, by exposure to ultraviolet or ionizing radiation, chemical mutagens, or viruses, or can be induced by the organism itself, by cellular processes such as hypermutation. In multicellular organisms with dedicated reproductive cells, mutations can be subdivided into germ line mutations, which can be passed on to descendants through the reproductive cells, and somatic mutations, which involve cells outside the dedicated reproductive group and which are not usually transmitted to descendants. If the organism can reproduce asexually through mechanisms such as cuttings or budding the distinction can become blurred. For example, plants can sometimes transmit somatic mutations to their descendants asexually or sexually where flower buds develop in somatically mutated parts of plants. A new mutation that was not inherited from either parent is called a de novo mutation. The source of the mutation is unrelated to the consequence, although the consequences are related to which cells were mutated.
Mutations create variation within the gene pool. Less favorable (or deleterious) mutations can be reduced in frequency in the gene pool by natural selection, while more favorable (beneficial or advantageous) mutations may accumulate and result in adaptive evolutionary changes. For example, a butterfly may produce offspring with new mutations. The majority of these mutations will have no effect; but one might change the color of one of the butterfly's offspring, making it harder (or easier) for predators to see. If this color change is advantageous, the chance of this butterfly surviving and producing its own offspring are a little better, and over time the number of butterflies with this mutation may form a larger percentage of the population.
Neutral mutations are defined as mutations whose effects do not influence the fitness of an individual. These can accumulate over time due to genetic drift. It is believed that the overwhelming majority of mutations have no significant effect on an organism's fitness. Also, DNA repair mechanisms are able to mend most changes before they become permanent mutations, and many organisms have mechanisms for eliminating otherwise permanently mutated somatic cells.
Mutation is generally accepted by the scientific community as the mechanism upon which natural selection acts, providing the advantageous new traits that survive and multiply in offspring or disadvantageous traits that die out with weaker organisms.
For more information about Mutation, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
News tagged with genetic changes
Genetic changes shown to be important indicators for disease progression in cervical cancer patients
Nov 13, 2009 |
not rated yet |
0
Cervical cancer patients with specific changes in the cancer genome have a three- or fourfold increased risk of relapse after standard treatment compared to patients without these changes, according to a study by Norwegian ...
Scientists launch effort to sequence the DNA of 10,000 vertebrates
Nov 04, 2009 |
5 / 5 (1) |
0
Scientists have an ambitious new strategy for untangling the evolutionary history of humans and their biological relatives: Create a genetic menagerie made of the DNA of more than 10,000 vertebrate species. The plan, proposed ...
Testicular tumors may explain why some diseases are more common in children of older fathers
Oct 25, 2009 |
4.3 / 5 (4) |
0
A rare form of testicular tumour has provided scientists with new insights into how genetic changes (mutations) arise in our children. The research, funded by the Wellcome Trust and the Danish Cancer Society, could explain ...
Woody plants adapted to past climate change more slowly than herbs
Sep 23, 2009 |
1 / 5 (1) |
1
Can we predict which species will be most vulnerable to climate change by studying how they responded in the past? A new study of flowering plants provides a clue. An analysis of more than 5000 plant species ...
Changing the course of nature: Are fisheries directing the evolution of fish populations?
Sep 10, 2009 |
2 / 5 (1) |
0
For many of the types of fish we buy in stores or order in restaurants, the chance that an individual dies from fishing is several times higher than dying of natural causes. This may seem obvious to most (they had to get ...
Study catches two bird populations as they split into seperate species
Jul 14, 2009 |
4.9 / 5 (9) |
2
A new study finds that a change in a single gene has sent two closely related bird populations on their way to becoming two distinct species. The study, published in the August issue of the American Naturalist, is one of ...
Genetic changes after Caesarean section may explain increased risk of developing disease
Jun 29, 2009 |
5 / 5 (1) |
0
(PhysOrg.com) -- Researchers at Karolinska Institutet have discovered that babies born by planned Caesarean section experience changes to the DNA pool in their white blood cells, which could be connected to altered stress ...
Aussie and Kiwi researchers make double MS genetic discovery
Jun 14, 2009 |
5 / 5 (1) |
0
Australian and New Zealand researchers have accelerated research into Multiple Sclerosis by discovering two new locations of genes which will help to unravel the causes of MS and other autoimmune disease.
Why can we talk? 'Humanized' mice speak volumes
May 28, 2009 |
3.5 / 5 (6) |
9
Mice carrying a "humanized version" of a gene believed to influence speech and language may not actually talk, but they nonetheless do have a lot to say about our evolutionary past, according to a report in the May 29th issue ...
New insight into primate eye evolution
May 18, 2009 |
5 / 5 (4) |
0
Researchers comparing the fetal development of the eye of the owl monkey with that of the capuchin monkey have found that only a minor difference in the timing of cell proliferation can explain the multiple anatomical differences ...
Natural protein may halt colorectal cancer's spread
Apr 21, 2009 |
not rated yet |
0
Medical College of Wisconsin Cancer Center researchers in Milwaukee have learned that a protein, CXCL12, that normally controls intestinal cell movement, has the potential to halt colorectal cancer spreading. These studies ...
Modern life's pressures may be hastening human evolution
Apr 13, 2009 |
4.7 / 5 (10) |
1
We're not finished yet. Even today, scientists say that human beings are continuing to evolve as our genes respond to rapid changes in the world around us. In fact, the pressures of modern life may be speeding up the pace ...
Is love at first sight real? Geneticists offer tantalizing clues
Apr 07, 2009 |
4.3 / 5 (3) |
0
Leave it to geneticists to answer a question that has perplexed humanity since the dawn of time: does love at first sight truly exist? According to a study published in the April 2009 issue of the journal Genetics, a team ...
Researchers take first look at the genetic dynamics of inbreeding depression
Mar 12, 2009 |
4.8 / 5 (4) |
0
Researchers have taken a first look at the broad genetic changes that accompany reproductive declines in inbred populations. Although scientists have known for more than a century that small populations of ...
'Undesirable' evolution can be reversed in fish, scientists show
Mar 03, 2009 |
5 / 5 (4) |
3
Intensive harvesting of the largest fish over many decades, while leaving the small fish behind, may have unintentionally genetically reprogrammed many species to grow smaller, said lead author Dr. David O. ...


