DNA sequence
hideA DNA sequence or genetic sequence is a succession of letters representing the primary structure of a real or hypothetical DNA molecule or strand, with the capacity to carry information as described by the central dogma of molecular biology.
The possible letters are A, C, G, and T, representing the four nucleotide bases of a DNA strand — adenine, cytosine, guanine, thymine — covalently linked to a phosphodiester backbone. In the typical case, the sequences are printed abutting one another without gaps, as in the sequence AAAGTCTGAC, read left to right in the 5' to 3' direction. Short sequences of nucleotides are referred to as oligonucleotides and are used in a range of laboratory applications in molecular biology. With regard to biological function, a DNA sequence may be considered sense or antisense, and either coding or noncoding. DNA sequences can also contain "junk DNA."
Sequences can be derived from the biological raw material through a process called DNA sequencing.
In some special cases, letters besides A, T, C, and G are present in a sequence. These letters represent ambiguity. Of all the molecules sampled, there is more than one kind of nucleotide at that position. The rules of the International Union of Pure and Applied Chemistry (IUPAC) are as follows:
For more information about DNA sequence, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
News tagged with genetic information
Hundreds of genes distinguish patients likely to survive advanced melanoma
Nov 09, 2009 |
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Although the chances of surviving advanced melanoma aren't very good with current therapies, some patients can live for years with cancer that has spread beyond the skin to other organs. Now it may be possible to identify ...
New discovery allows scientists for the first time to experimentally annotate genomes
Nov 09, 2009 |
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Over the last 20 years, the sequencing of the human genome, along with related organisms, has represented one of the largest scientific endeavors in the history of mankind. The information collected from genome ...
Research team establishes family tree for cattle, other ruminants
Oct 19, 2009 |
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Pairing a new approach to prepare ancient DNA with a new scientific technique developed specifically to genotype a cow, an MU animal scientist, along with a team of international researchers, created a very ...
Trimming the Tree of Life
Oct 08, 2009 |
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(PhysOrg.com) -- In a sense, Antonis Rokas is an arborist: He is a member of a small cadre to scientists who are applying the growing power of genomics to untangle and correctly arrange the branches of the ...
Keeping DNA 'all in the family'
Oct 06, 2009 |
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Scientists look for clues about therapies and cures for life-threatening childhood illnesses in children's DNA -- it seems only logical to do so. But the decision as to who should have access to DNA samples from children ...
IBM Research Aims to Build Nanoscale DNA Sequencer (w/ Video)
Nanotechnology / Bio & Medicine
Oct 06, 2009 |
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(PhysOrg.com) -- In an effort to build a nanoscale DNA sequencer, IBM scientists are drilling nano-sized holes in computer-like chips and passing DNA strands through them in order to read the information contained ...
New route to leukemia uncovered
Sep 28, 2009 |
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(PhysOrg.com) -- Scientists have discovered a completely new route by which leukaemia develops, according to research published in Nature this weekend.
Girl's rare form of diabetes leads to injection-free treatment for some
Sep 23, 2009 |
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Three years after she made medical history and was freed from painful insulin injections, 9-year-old Lilly Jaffe is just beginning to understand how much her story changed the course of diabetes research and treatment.
Researchers working to develop, market embryonic test for bovine genetics
Sep 17, 2009 |
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(PhysOrg.com) -- Looking at the genetic makeup of cattle to determine their value is nothing new. An examination of a small sample of hair or blood can reveal if a calf has any genetic diseases that will lower ...
DNA pioneer appeals for cuts to criminal database
Sep 10, 2009 |
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(AP) -- Like so many great discoveries, it was an accident. British scientist Alec Jeffreys realized 25 years ago Thursday that individuals have "DNA fingerprints," unique patterns of genetic material that ...
Fear of insurance rejection deters potentially life saving genetic tests for bowel cancer
Sep 06, 2009 |
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An Australian study of families with genetic risk of bowel cancer has found that 50 percent of participants declined genetic testing when informed of insurance implications.
Genes in prevention: Hopes and doubts
Aug 31, 2009 |
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At present almost every month there are papers reporting the discovery of new genetic variants that affect the risk of coronary artery disease and heart attacks. This is a truly exciting time for both researchers and clinicians ...
'Jumping genes' create antibiotic resistance in bacteria
Aug 20, 2009 |
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(PhysOrg.com) -- A small piece of foreign DNA recognizes when and where to slip into a bacterium's genetic code, allowing bacteria to genetically adapt to their environment -- and develop resistance to antibiotics, ...
Professor sequences his entire genome at low cost, with small team
Aug 10, 2009 |
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(PhysOrg.com) -- The first few times that scientists mapped out all the DNA in a human being in 2001, each effort cost hundreds of millions of dollars and involved more than 250 people. Even last year, when ...
Understanding how weeds are resistant to herbicides
Aug 05, 2009 |
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In a little over seven hours, University of Illinois weed scientist Patrick Tranel got more genetic information about waterhemp than in two years time in a lab. The genetic information was obtained using pyrosequencing technology ...
