News tagged with genetic pathway
Neurobiologists identify animal model for a deadly human metabolic disorder
In medical research, finding a reliable and cost-effective animal model can greatly enhance success in identifying disease mechanisms and genetic pathways, potentially cutting years off drug testing regimes and development ...
Medicine & Health / Neuroscience
10 hours ago |
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Jak of all trades? Not of leukaemia therapy
About one in five or six cases of adult leukaemia in Western populations relates to so-called chronic myeloid leukaemia, or CML. Treatment of CML usually relies on inhibitors of the abnormal protein that causes the condition ...
Jan 30, 2012 |
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Gene research sheds light on timing of menopause
(Medical Xpress) -- An international team of researchers has discovered 13 new regions of the genome associated with the timing of menopause.
Jan 23, 2012 |
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Signaling to chromatin
(Medical Xpress) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI) in collaboration with their colleagues from the Department of Biosystems Science and Engineering of the ETH ...
Jan 03, 2012 |
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Is obesity a ciliopathy, triggered by malfunctioning primary cilia?
Is obesity a ciliopathy, a disorder such as polycystic kidney disease (PKD), which is triggered by a defect in the microscopic hair-like cilia that protrude from virtually every cell of humans and other vertebrates?
Dec 06, 2011 |
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Aging human bodies and aging human oocytes run on different clocks
Reproductive and somatic aging use different molecular mechanisms that show little overlap between the types of genes required to keep oocytes healthy and the genes that generally extend life span, according to Coleen Murphy, ...
Dec 06, 2011 |
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Unlocking the genetic and molecular mystery of soft-tissue sarcoma
Scientists at Joslin Diabetes Center in Boston have uncovered important molecular and genetic keys to the development of soft-tissue sarcomas in skeletal muscle, giving researchers and clinicians additional targets to stop ...
Nov 30, 2011 |
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Cleft lip corrected genetically in mouse model
Scientists at Weill Cornell Medical College used genetic methods to successfully repair cleft lips in mice embryos specially engineered for the study of cleft lip and cleft palate. The research breakthrough may show the way ...
Nov 28, 2011 |
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Surprising pathway implicated in stuttering
Researchers at Washington University School of Medicine in St. Louis have obtained new evidence that at least some persistent stuttering is caused by mutations in a gene governing not speech, but a metabolic pathway involved ...
Nov 22, 2011 |
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Worms reveal secrets of wound-healing response
The lowly and simple roundworm may be the ideal laboratory model to learn more about the complex processes involved in repairing wounds and could eventually allow scientists to improve the body's response to healing skin ...
Nov 17, 2011 |
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New ADHD findings
A combination of rare and common genetic variations could play a part in biological pathways linked to Attention Deficit Hyperactivity Disorder (ADHD).
Medicine & Health / Psychology & Psychiatry
Nov 14, 2011 |
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Signaling pathway linked to inflammatory breast cancer may drive disease metastasis
Amplification of anaplastic lymphoma kinase, which has been reported in other cancers such as non-small cell lung cancers, may be a primary driver of the rapid metastasis that patients with inflammatory breast cancer experience.
Nov 13, 2011 |
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Researchers discover genes involved in colorectal cancer
A jumping gene with the fairy tale name "Sleeping Beauty" has helped to unlock vital clues for researchers investigating the genetics of colorectal cancer.
Nov 06, 2011 |
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Genome-scale network of rice genes to speed the development of biofuel crops
The first genome-scale model for predicting the functions of genes and gene networks in a grass species has been developed by an international team of researches that includes scientists with the U.S. Department ...
Nov 02, 2011 |
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Study identifies genetic basis of human metabolic individuality
In what is so far the largest investigation of its kind, researchers uncovered a wide range of new insights about common diseases and how they are affected by differences between two persons' genes. The results from this ...
Oct 26, 2011 |
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