DNA sequence

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A DNA sequence or genetic sequence is a succession of letters representing the primary structure of a real or hypothetical DNA molecule or strand, with the capacity to carry information as described by the central dogma of molecular biology.

The possible letters are A, C, G, and T, representing the four nucleotide bases of a DNA strand — adenine, cytosine, guanine, thymine — covalently linked to a phosphodiester backbone. In the typical case, the sequences are printed abutting one another without gaps, as in the sequence AAAGTCTGAC, read left to right in the 5' to 3' direction. Short sequences of nucleotides are referred to as oligonucleotides and are used in a range of laboratory applications in molecular biology. With regard to biological function, a DNA sequence may be considered sense or antisense, and either coding or noncoding. DNA sequences can also contain "junk DNA."

Sequences can be derived from the biological raw material through a process called DNA sequencing.

In some special cases, letters besides A, T, C, and G are present in a sequence. These letters represent ambiguity. Of all the molecules sampled, there is more than one kind of nucleotide at that position. The rules of the International Union of Pure and Applied Chemistry (IUPAC) are as follows:

For more information about DNA sequence, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.


News tagged with genetic sequence

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Study reveals H1N1 unexpected weakness

Study reveals H1N1 unexpected weakness

Medicine & Health / Research

created Dec 10, 2009 | popularity 4.8 / 5 (19) | comments 7

The H1N1 influenza virus has been keeping a secret that may be the key to defeating it and other flu viruses as well.


Scientists unlock clues for tailoring corn plant for food, energy needs

Biology / Biotechnology

created Nov 19, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- Scientists have long known that the offspring of two inbred strains tend to be superior to both their parents. Now, a team of researchers including a University of Florida geneticist has discovered clues ...


Why do human populations differ? Fruit fly study aims to provide genetic answers

Biology / Other

created Oct 13, 2009 | popularity 3.5 / 5 (2) | comments 0

(PhysOrg.com) -- Charles Aquadro, professor of molecular biology and genetics, researches how fruit flies provide clues to humans' own genetic footprints of adaptation.


Keeping DNA 'all in the family'

Medicine & Health / Genetics

created Oct 06, 2009 | popularity 4 / 5 (1) | comments 0

Scientists look for clues about therapies and cures for life-threatening childhood illnesses in children's DNA -- it seems only logical to do so. But the decision as to who should have access to DNA samples from children ...


DNA detector

Rapid DNA Detection Quickly Diagnoses Infections

Nanotechnology / Bio & Medicine

created Oct 05, 2009 | popularity 4.8 / 5 (4) | comments 0

(PhysOrg.com) -- A new portable device can detect bacteria and help prevent the spread of infectious diseases. This new tool takes from 15 minutes to 2 hours to diagnose a patient for infectious diseases and ...


The first DNA barcodes of commonly traded bushmeat are published

The first DNA barcodes of commonly traded bushmeat are published

Biology / Biotechnology

created Sep 04, 2009 | popularity not rated yet | comments 0

Leather handbags and chunks of red meat: when wildlife specialists find these items in shipping containers, luggage, or local markets, they can now use newly published genetic sequences known as "DNA barcodes" ...


HIV subtype linked to increased likelihood for dementia

Medicine & Health / HIV & AIDS

created Aug 28, 2009 | popularity not rated yet | comments 0

Patients infected with a particular subtype of HIV, the virus that causes AIDS, are more likely to develop dementia than patients with other subtypes, a study led by Johns Hopkins researchers shows. The finding, reported ...


Online Encyclopedia of Life reaches 150,000 species

Online Encyclopedia of Life reaches 150,000 species

Biology / Plants & Animals

created Aug 25, 2009 | popularity 4.8 / 5 (6) | comments 0

The public and scientists have helped create the first 150,000 species pages in the Encyclopedia of Life (EOL), the global online project to create a page for each of the 1.8 million known species on the planet.


Understanding how weeds are resistant to herbicides

Biology / Ecology

created Aug 05, 2009 | popularity not rated yet | comments 0

In a little over seven hours, University of Illinois weed scientist Patrick Tranel got more genetic information about waterhemp than in two years time in a lab. The genetic information was obtained using pyrosequencing technology ...


After dinosaurs, mammals rise but their genomes get smaller

Biology / Evolution

created Jul 27, 2009 | popularity 4.5 / 5 (2) | comments 1

(PhysOrg.com) -- Evidence buried in the chromosomes of animals and plants strongly suggests only one group -- mammals -- have seen their genomes shrink after the dinosaurs' extinction. What's more, that trend continues today, ...


Genomes of parasitic flatworms decoded

Genomes of parasitic flatworms decoded

Biology / Biotechnology

created Jul 15, 2009 | popularity not rated yet | comments 0

Two international research teams have determined the complete genetic sequences of two species of parasitic flatworms that cause schistosomiasis, a debilitating condition also known as snail fever. Schistosoma ma ...


Arizona researchers to sequence West African rice strain

Biology / Biotechnology

created Jul 13, 2009 | popularity not rated yet | comments 0

A $1.5 million grant from the National Science Foundation will allow University of Arizona researchers to unlock the genetic code of West African cultivated rice - and along the way to gain knowledge that could help commercial ...


Gene evolution process discovered

Biology / Cell & Microbiology

created Jun 15, 2009 | popularity 4.4 / 5 (5) | comments 0

One of the mechanisms governing how our physical features and behavioural traits have evolved over centuries has been discovered by researchers at the University of Leeds.


Found: 1 in 3 billion

Medicine & Health / Cancer

created Jun 11, 2009 | popularity 5 / 5 (3) | comments 0

Vancouver scientists from the Ovarian Cancer Research (OvCaRe) Program at BC Cancer Agency and Vancouver Coastal Health Research Institute have discovered that there appears to be a single spelling mistake in the genetic ...


Researchers find snippet of RNA that helps make individuals remarkably alike

Biology / Cell & Microbiology

created May 05, 2009 | popularity 4.3 / 5 (4) | comments 0

"No two people are alike." Yet when we consider the thousands of genes with frequent differences in genetic composition among different people, it is remarkable how much alike we are.