Genome

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In classical genetics, the genome of a diploid organism including eukarya refers to a full set of chromosomes or genes in a gamete; thereby, a regular somatic cell contains two full sets of genomes. In haploid organisms, including bacteria, archaea, viruses, and mitochondria, a cell contains only a single set of the genome, usually in a single circular or contiguous linear DNA (or RNA for retroviruses). In modern molecular biology the genome of an organism is its hereditary information encoded in DNA (or, for retroviruses, RNA).

The genome includes both the genes and the non-coding sequences of the DNA. The term was adapted in 1920 by Hans Winkler, Professor of Botany at the University of Hamburg, Germany. The Oxford English Dictionary suggests the name to be a portmanteau of the words gene and chromosome; however, many related -ome words already existed, such as biome and rhizome, forming a vocabulary into which genome fits systematically.

More precisely, the genome of an organism is a complete genetic sequence on one set of chromosomes; for example, one of the two sets that a diploid individual carries in every somatic cell. The term genome can be applied specifically to mean that stored on a complete set of nuclear DNA (i.e., the "nuclear genome") but can also be applied to that stored within organelles that contain their own DNA, as with the mitochondrial genome or the chloroplast genome. Additionally, the genome can comprise nonchromosomal genetic elements such as viruses, plasmids, and transposable elements. When people say that the genome of a sexually reproducing species has been "sequenced", typically they are referring to a determination of the sequences of one set of autosomes and one of each type of sex chromosome, which together represent both of the possible sexes. Even in species that exist in only one sex, what is described as "a genome sequence" may be a composite read from the chromosomes of various individuals. In general use, the phrase "genetic makeup" is sometimes used conversationally to mean the genome of a particular individual or organism. The study of the global properties of genomes of related organisms is usually referred to as genomics, which distinguishes it from genetics which generally studies the properties of single genes or groups of genes.

Both the number of base pairs and the number of genes vary widely from one species to another, and there is little connection between the two (an observation known as the C-value paradox). At present, the highest known number of genes is around 60,000, for the protozoan causing trichomoniasis (see List of sequenced eukaryotic genomes), almost three times as many as in the human genome.

An analogy to the human genome stored on DNA is that of instructions stored in a book:

For more information about Genome, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.


News tagged with genome sequence

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Antarctic lake

Antarctic lake home to diverse community of viruses

Biology / Cell & Microbiology

created Nov 11, 2009 | popularity 4.9 / 5 (17) | comments 1

(PhysOrg.com) -- A study of the genetic structure of viruses in an Antarctic lake has revealed an astonishing genetic richness in the large number of viral families discovered.


New discovery allows scientists for the first time to experimentally annotate genomes

New discovery allows scientists for the first time to experimentally annotate genomes

Biology / Biotechnology

created Nov 09, 2009 | popularity 5 / 5 (6) | comments 0

Over the last 20 years, the sequencing of the human genome, along with related organisms, has represented one of the largest scientific endeavors in the history of mankind. The information collected from genome ...


Petascale computing tools could provide deeper insight into genomic evolution

Petascale computing tools could provide deeper insight into genomic evolution

Technology / Computer Sciences

created Nov 17, 2009 | popularity 5 / 5 (3) | comments 0

Technological advances in high-throughput DNA sequencing have opened up the possibility of determining how living things are related by analyzing the ways in which their genes have been rearranged on chromosomes. ...





Search results for genome sequence


Researchers complete draft genome sequence for cassava

Biology / Biotechnology

created Nov 09, 2009 | popularity not rated yet | comments 0

A team of academic, government and industry researchers has completed a first draft of the cassava (Manihot esculenta) genome. The project is an important first step in accelerating the pace of research on this subsistence ...


maize

Reference Genome of Maize Published (w/ Podcast)

Biology / Biotechnology

created Nov 19, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- A four-year, multi-institutional effort co-led by three Cold Spring Harbor Laboratory scientists culminated today in publication of a landmark series of papers in the journal Science reveal ...


Genome advances promise personalized medical treatment

Medicine & Health / Genetics

created Nov 18, 2009 | popularity 5 / 5 (2) | comments 1

A whirlwind of activity is under way to apply the findings of the $3 billion Human Genome Project to improve health care in the United States and around the world.


Biology of emergent Salmonella exposed

Biology of emergent Salmonella exposed

Biology / Biotechnology

created Nov 30, 2009 | popularity 5 / 5 (1) | comments 0

Researchers have characterised a new multi drug resistant strain of Salmonella Typhimurium that is causing life-threatening disease in Africa.


Gene Hijacked By HIV Ancestor Suggests New Way to Block Viral Reproduction

Gene Hijacked By HIV Ancestor Suggests New Way to Block Viral Reproduction

Biology / Cell & Microbiology

created 4 hours ago | popularity 5 / 5 (2) | comments 0

(PhysOrg.com) -- An ancestor of the AIDS virus hijacked an entire gene, perhaps from some prehistoric cat it had infected, a gene that makes it much better able to infect humans, according to a study published ...


UGA researchers lead team in discovery involving devastating freshwater fish parasite, 'Ich'

Discovery opens new avenues for treating devastating freshwater fish parasite, 'Ich'

Biology / Cell & Microbiology

created Dec 02, 2009 | popularity 4.8 / 5 (4) | comments 0

Researchers from the University of Georgia College of Veterinary Medicine have made an "unexpected" dual discovery that could open new avenues for treating Ichthyophthirius multifiliis, or "Ich", a devastating ...


New tools for prediction of disease progression in acute childhood leukemia

Medicine & Health / Cancer

created Nov 27, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- Researchers at Uppsala University and University Children’s Hospital in Uppsala have devised powerful new tools for typing cells from children with acute lymphatic leukemia and for prediction of how children ...


PLoS Genetics 2009 maize genome collection

Biology / Biotechnology

created Nov 19, 2009 | popularity not rated yet | comments 0

Maize is an important crop in many countries of the world. It is widely used for human consumption, animal feed, and industrial materials. It also is considered an exemplar plant species for studying domestication, molecular ...


Scientists identify DNA that regulates antibody production

Medicine & Health / Research

created Nov 20, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- When foreign invaders trip the immune system’s alarm, antibodies need to be specially sculpted to attack them head on. New research now shows that gene segments called enhancers control the reshuffling of ...


Transcription factors guide differences in human and chimp brain function

Transcription factors guide differences in human and chimp brain function

Biology / Cell & Microbiology

created 5 hours ago | popularity 5 / 5 (1) | comments 0

Humans share at least 97 percent of their genes with chimpanzees, but, as a new study of transcription factors makes clear, what you have in your genome may be less important than how you use it.



List of search results for genome sequence