Genome
hideIn classical genetics, the genome of a diploid organism including eukarya refers to a full set of chromosomes or genes in a gamete; thereby, a regular somatic cell contains two full sets of genomes. In haploid organisms, including bacteria, archaea, viruses, and mitochondria, a cell contains only a single set of the genome, usually in a single circular or contiguous linear DNA (or RNA for retroviruses). In modern molecular biology the genome of an organism is its hereditary information encoded in DNA (or, for retroviruses, RNA).
The genome includes both the genes and the non-coding sequences of the DNA. The term was adapted in 1920 by Hans Winkler, Professor of Botany at the University of Hamburg, Germany. The Oxford English Dictionary suggests the name to be a portmanteau of the words gene and chromosome; however, many related -ome words already existed, such as biome and rhizome, forming a vocabulary into which genome fits systematically.
More precisely, the genome of an organism is a complete genetic sequence on one set of chromosomes; for example, one of the two sets that a diploid individual carries in every somatic cell. The term genome can be applied specifically to mean that stored on a complete set of nuclear DNA (i.e., the "nuclear genome") but can also be applied to that stored within organelles that contain their own DNA, as with the mitochondrial genome or the chloroplast genome. Additionally, the genome can comprise nonchromosomal genetic elements such as viruses, plasmids, and transposable elements. When people say that the genome of a sexually reproducing species has been "sequenced", typically they are referring to a determination of the sequences of one set of autosomes and one of each type of sex chromosome, which together represent both of the possible sexes. Even in species that exist in only one sex, what is described as "a genome sequence" may be a composite read from the chromosomes of various individuals. In general use, the phrase "genetic makeup" is sometimes used conversationally to mean the genome of a particular individual or organism. The study of the global properties of genomes of related organisms is usually referred to as genomics, which distinguishes it from genetics which generally studies the properties of single genes or groups of genes.
Both the number of base pairs and the number of genes vary widely from one species to another, and there is little connection between the two (an observation known as the C-value paradox). At present, the highest known number of genes is around 60,000, for the protozoan causing trichomoniasis (see List of sequenced eukaryotic genomes), almost three times as many as in the human genome.
An analogy to the human genome stored on DNA is that of instructions stored in a book:
For more information about Genome, read the full article at
Wikipedia.
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News tagged with genome
Genetic studies reveal new causes of severe obesity in childhood
17 hours ago |
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Scientists in Cambridge have discovered that the loss of a key segment of DNA can lead to severe childhood obesity. This is the first study to show that this kind of genetic alteration can cause obesity. The results are published ...
Researchers identify proteins in lung cancer cells that may provide potential drug targets
Nov 25, 2009 |
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Researchers from Boston University School of Medicine (BUSM) and the Boston University Biomedical Engineering Department have identified a number of proteins whose activation allows them to distinguish between cancer and ...
Ancestry attracts, but love is blind
Nov 20, 2009 |
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People preferentially marry those with similar ancestry, but their decisions are not necessarily based on hair, eye or skin colour. Research, published in BioMed Central's open access journal Genome Biology, shows that M ...
PLoS Genetics 2009 maize genome collection
Nov 19, 2009 |
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Maize is an important crop in many countries of the world. It is widely used for human consumption, animal feed, and industrial materials. It also is considered an exemplar plant species for studying domestication, molecular ...
Reference Genome of Maize Published (w/ Podcast)
Nov 19, 2009 |
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(PhysOrg.com) -- A four-year, multi-institutional effort co-led by three Cold Spring Harbor Laboratory scientists culminated today in publication of a landmark series of papers in the journal Science reveal ...
Scientists unlock clues for tailoring corn plant for food, energy needs
Nov 19, 2009 |
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(PhysOrg.com) -- Scientists have long known that the offspring of two inbred strains tend to be superior to both their parents. Now, a team of researchers including a University of Florida geneticist has discovered clues ...
Technique finds gene regulatory sites without knowledge of regulators
Nov 19, 2009 |
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A new statistical technique developed by researchers at the University of Illinois allows scientists to scan a genome for specific gene-regulatory regions without requiring prior knowledge of the relevant transcription factors. ...
Genome advances promise personalized medical treatment
Nov 18, 2009 |
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A whirlwind of activity is under way to apply the findings of the $3 billion Human Genome Project to improve health care in the United States and around the world.
Petascale computing tools could provide deeper insight into genomic evolution
Technology / Computer Sciences
Nov 17, 2009 |
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Technological advances in high-throughput DNA sequencing have opened up the possibility of determining how living things are related by analyzing the ways in which their genes have been rearranged on chromosomes. ...
Scientists put interactive flu tracking at public's fingertips
Nov 16, 2009 |
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New methods of studying avian influenza strains and visually mapping their movement around the world will help scientists more quickly learn the behavior of the pandemic H1N1 flu virus, Ohio State University ...
Two proteins act as molecular tailors in DNA repair
Nov 13, 2009 |
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(PhysOrg.com) -- On average, our cells encounter a very lethal form of DNA damage 10 times a day. Lucky for us, we have the capacity to repair each and every one of them. New research now reveals exactly how two well-known ...
Genetic changes shown to be important indicators for disease progression in cervical cancer patients
Nov 13, 2009 |
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Cervical cancer patients with specific changes in the cancer genome have a three- or fourfold increased risk of relapse after standard treatment compared to patients without these changes, according to a study by Norwegian ...
Hoping for a fluorescent basket case: How HIV is assembled and released from infected cells
Nov 12, 2009 |
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Although recent advances have raised hopes that a protective vaccine can be developed, acquired immunodeficiency syndrome (AIDS) remains a major public health problem. Much has been learned about HIV-1, the virus that causes ...
Antarctic lake home to diverse community of viruses
Nov 11, 2009 |
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(PhysOrg.com) -- A study of the genetic structure of viruses in an Antarctic lake has revealed an astonishing genetic richness in the large number of viral families discovered.
Ancient penguin DNA raises doubts about accuracy of genetic dating techniques
Nov 10, 2009 |
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Penguins that died 44,000 years ago in Antarctica have provided extraordinary frozen DNA samples that challenge the accuracy of traditional genetic aging measurements, and suggest those approaches have been ...
